Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative Review
Antiphospholipid syndrome (APS) is a common autoimmune pro-thrombotic condition characterised by thrombosis and pregnancy morbidity. There are a broad range of neuropsychiatric manifestations associated with APS, from focal symptoms to more global dysfunction. Patients commonly present with transien...
| Autores principales: | , |
|---|---|
| Formato: | Artículo |
| Lenguaje: | English |
| Publicado: |
MDPI AG
2022-01-01
|
| Colección: | Brain Sciences |
| Materias: | |
| Acceso en línea: | https://www.mdpi.com/2076-3425/12/1/91 |
| _version_ | 1827666238722015232 |
|---|---|
| author | Yik Long Man Giovanni Sanna |
| author_facet | Yik Long Man Giovanni Sanna |
| author_sort | Yik Long Man |
| collection | DOAJ |
| description | Antiphospholipid syndrome (APS) is a common autoimmune pro-thrombotic condition characterised by thrombosis and pregnancy morbidity. There are a broad range of neuropsychiatric manifestations associated with APS, from focal symptoms to more global dysfunction. Patients commonly present with transient ischaemic attacks and ischaemic strokes, with identifiable lesions on brain imaging. However, the underlying pathogenesis remains uncertain in other manifestations, such as cognitive dysfunction, seizures, headache and chorea. The aim is to provide a comprehensive review of the various neuropsychiatric manifestations associated with APS. A detailed literature search was applied to PubMed, including citations from 1983 to December 2021. |
| first_indexed | 2024-03-10T01:47:58Z |
| format | Article |
| id | doaj.art-457cff9dd67b4534bef3f955d38d1247 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T01:47:58Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-457cff9dd67b4534bef3f955d38d12472023-11-23T13:09:59ZengMDPI AGBrain Sciences2076-34252022-01-011219110.3390/brainsci12010091Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative ReviewYik Long Man0Giovanni Sanna1Louise Coote Lupus Unit, Guy’s and St Thomas’ NHS Foundation Trust, London SE1 9RT, UKLouise Coote Lupus Unit, Guy’s and St Thomas’ NHS Foundation Trust, London SE1 9RT, UKAntiphospholipid syndrome (APS) is a common autoimmune pro-thrombotic condition characterised by thrombosis and pregnancy morbidity. There are a broad range of neuropsychiatric manifestations associated with APS, from focal symptoms to more global dysfunction. Patients commonly present with transient ischaemic attacks and ischaemic strokes, with identifiable lesions on brain imaging. However, the underlying pathogenesis remains uncertain in other manifestations, such as cognitive dysfunction, seizures, headache and chorea. The aim is to provide a comprehensive review of the various neuropsychiatric manifestations associated with APS. A detailed literature search was applied to PubMed, including citations from 1983 to December 2021.https://www.mdpi.com/2076-3425/12/1/91antiphospholipid syndromeantiphospholipid antibodiesneurological manifestationspsychiatric manifestations |
| spellingShingle | Yik Long Man Giovanni Sanna Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative Review Brain Sciences antiphospholipid syndrome antiphospholipid antibodies neurological manifestations psychiatric manifestations |
| title | Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative Review |
| title_full | Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative Review |
| title_fullStr | Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative Review |
| title_full_unstemmed | Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative Review |
| title_short | Neuropsychiatric Manifestations of Antiphospholipid Syndrome—A Narrative Review |
| title_sort | neuropsychiatric manifestations of antiphospholipid syndrome a narrative review |
| topic | antiphospholipid syndrome antiphospholipid antibodies neurological manifestations psychiatric manifestations |
| url | https://www.mdpi.com/2076-3425/12/1/91 |
| work_keys_str_mv | AT yiklongman neuropsychiatricmanifestationsofantiphospholipidsyndromeanarrativereview AT giovannisanna neuropsychiatricmanifestationsofantiphospholipidsyndromeanarrativereview |