Blast Exposure Induces Acute Alterations in Circadian Clock Genes in the Hypothalamus and Pineal Gland in Rats: An Exploratory Study

Blast Exposure Induces Acute Alterations in Circadian Clock Genes in the Hypothalamus and Pineal Gland in Rats: An Exploratory Study

Blast-induced traumatic brain injury (bTBI) frequently results in sleep and circadian rhythm disturbances. We have investigated whether dysregulation of circadian rhythm after bTBI is mediated by dysregulation of clock genes in the hypothalamus and pineal gland of rats at acute (24?h) and chronic (1...

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Bibliographic Details
Main Authors: Manoj Govindarajulu, Mital Y. Patel, Jishnu Krishnan, Joseph B. Long, Peethambaran Arun
Format: Article
Language:English
Published: Mary Ann Liebert 2023-08-01
Series:Neurotrauma Reports
Subjects:
blast injury
circadian rhythm
clock genes
hypocretin
hypothalamus
pineal gland
Online Access:https://www.liebertpub.com/doi/full/10.1089/NEUR.2023.0048

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