Selective sensitization of C-fiber nociceptors by hydrogen sulfide

Selective sensitization of C-fiber nociceptors by hydrogen sulfide

We examined the effects of intraplantar (i.pl.) administration of NaHS, an H2S donor, known to cause T-type Ca2+ channel (T-channel)-dependent mechanical hyperalgesia, on responsiveness to electric stimulation with 5, 250 and 2000 Hz sine waves (SW) that selectively excites C, Aδ and Aβ fibers, resp...

Full description

Bibliographic Details
Main Authors: Yuka Aoki, Maho Tsubota, Yuta Nishimoto, Yumi Maeda, Fumiko Sekiguchi, Atsufumi Kawabata
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Journal of Pharmacological Sciences
Subjects:
T-type calcium channel
Hydrogen sulfide
C-fiber nociceptor
Online Access:http://www.sciencedirect.com/science/article/pii/S134786131500256X

Similar Items

Similar Items