Partial Versus Total Omentectomy in Patients with Gastric Cancer: A Systemic Review and Meta-Analysis
<i>Background:</i> Surgical treatment is the key to cure localized gastric cancer. There is no strong evidence that supports the value of omentectomy. Thus, a meta-analysis was conducted to compare the safety and efficiency of partial and total omentectomy in patients with gastric cancer...
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MDPI AG
2021-10-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/13/19/4971 |
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| author | Shion Wei Chai Suo-Hsien Wang Chih-Yuan Wang Yi-Chan Chen Ruey-Shyang Soong Ting-Shuo Huang |
| author_facet | Shion Wei Chai Suo-Hsien Wang Chih-Yuan Wang Yi-Chan Chen Ruey-Shyang Soong Ting-Shuo Huang |
| author_sort | Shion Wei Chai |
| collection | DOAJ |
| description | <i>Background:</i> Surgical treatment is the key to cure localized gastric cancer. There is no strong evidence that supports the value of omentectomy. Thus, a meta-analysis was conducted to compare the safety and efficiency of partial and total omentectomy in patients with gastric cancer. <i>Methods:</i> PubMed, Embase, and Cochrane Library databases were searched. All studies that compared total and partial omentectomy as treatments for gastric cancer were included. The primary outcomes were patients’ overall survival and disease-free survival, while the secondary outcomes were perioperative outcome and postoperative complications. <i>Results:</i> A total of nine studies were examined, wherein 1043 patients were included in the partial omentectomy group, and 1995 in the total omentectomy group. The partial omentectomy group was associated with better overall survival (hazard ratio: 0.80, 95% CI: 0.66 to 0.98, <i>p</i> = 0.04, <i>I<sup>2</sup></i> = 0%), shorter operative time, and lesser blood loss than the total omentectomy group. In addition, no statistically significant difference was observed in the number of dissected lymph nodes, length of hospital stays, complication rate, and disease-free survival. <i>Conclusions:</i> Our results show that, compared with total omentectomy in gastric cancer surgery, partial omentectomy had non-inferior oncological outcomes and comparable safety outcomes. |
| first_indexed | 2024-03-10T07:04:39Z |
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| id | doaj.art-4584a2e740764600ac67d70fdd6e2e2f |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T07:04:39Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-4584a2e740764600ac67d70fdd6e2e2f2023-11-22T15:55:05ZengMDPI AGCancers2072-66942021-10-011319497110.3390/cancers13194971Partial Versus Total Omentectomy in Patients with Gastric Cancer: A Systemic Review and Meta-AnalysisShion Wei Chai0Suo-Hsien Wang1Chih-Yuan Wang2Yi-Chan Chen3Ruey-Shyang Soong4Ting-Shuo Huang5Division of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Keelung Branch, No. 222, Mai-Chin Road, Keelung 20401, TaiwanDivision of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Keelung Branch, No. 222, Mai-Chin Road, Keelung 20401, TaiwanDivision of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Keelung Branch, No. 222, Mai-Chin Road, Keelung 20401, TaiwanDivision of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Keelung Branch, No. 222, Mai-Chin Road, Keelung 20401, TaiwanDivision of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Keelung Branch, No. 222, Mai-Chin Road, Keelung 20401, TaiwanDivision of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Keelung Branch, No. 222, Mai-Chin Road, Keelung 20401, Taiwan<i>Background:</i> Surgical treatment is the key to cure localized gastric cancer. There is no strong evidence that supports the value of omentectomy. Thus, a meta-analysis was conducted to compare the safety and efficiency of partial and total omentectomy in patients with gastric cancer. <i>Methods:</i> PubMed, Embase, and Cochrane Library databases were searched. All studies that compared total and partial omentectomy as treatments for gastric cancer were included. The primary outcomes were patients’ overall survival and disease-free survival, while the secondary outcomes were perioperative outcome and postoperative complications. <i>Results:</i> A total of nine studies were examined, wherein 1043 patients were included in the partial omentectomy group, and 1995 in the total omentectomy group. The partial omentectomy group was associated with better overall survival (hazard ratio: 0.80, 95% CI: 0.66 to 0.98, <i>p</i> = 0.04, <i>I<sup>2</sup></i> = 0%), shorter operative time, and lesser blood loss than the total omentectomy group. In addition, no statistically significant difference was observed in the number of dissected lymph nodes, length of hospital stays, complication rate, and disease-free survival. <i>Conclusions:</i> Our results show that, compared with total omentectomy in gastric cancer surgery, partial omentectomy had non-inferior oncological outcomes and comparable safety outcomes.https://www.mdpi.com/2072-6694/13/19/4971gastric cancergastrectomytotal omentectomypartial omentectomysurvival |
| spellingShingle | Shion Wei Chai Suo-Hsien Wang Chih-Yuan Wang Yi-Chan Chen Ruey-Shyang Soong Ting-Shuo Huang Partial Versus Total Omentectomy in Patients with Gastric Cancer: A Systemic Review and Meta-Analysis Cancers gastric cancer gastrectomy total omentectomy partial omentectomy survival |
| title | Partial Versus Total Omentectomy in Patients with Gastric Cancer: A Systemic Review and Meta-Analysis |
| title_full | Partial Versus Total Omentectomy in Patients with Gastric Cancer: A Systemic Review and Meta-Analysis |
| title_fullStr | Partial Versus Total Omentectomy in Patients with Gastric Cancer: A Systemic Review and Meta-Analysis |
| title_full_unstemmed | Partial Versus Total Omentectomy in Patients with Gastric Cancer: A Systemic Review and Meta-Analysis |
| title_short | Partial Versus Total Omentectomy in Patients with Gastric Cancer: A Systemic Review and Meta-Analysis |
| title_sort | partial versus total omentectomy in patients with gastric cancer a systemic review and meta analysis |
| topic | gastric cancer gastrectomy total omentectomy partial omentectomy survival |
| url | https://www.mdpi.com/2072-6694/13/19/4971 |
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