Variant Aldehyde Dehydrogenase 2 (ALDH2*2) Is a Risk Factor for Coronary Spasm and ST‐Segment Elevation Myocardial Infarction

Variant Aldehyde Dehydrogenase 2 (ALDH2*2) Is a Risk Factor for Coronary Spasm and ST‐Segment Elevation Myocardial Infarction

BackgroundMitochondrial aldehyde dehydrogenase 2 (ALDH2) plays a key role in removing toxic aldehydes. Deficient variant ALDH2*2 genotype is prevalent in up to 40% of the East Asians and reported to be associated with acute myocardial infarction (AMI). To elucidate the mechanisms underlying the asso...

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Bibliographic Details
Main Authors: Yuji Mizuno, Seiji Hokimoto, Eisaku Harada, Kenji Kinoshita, Kazuko Nakagawa, Michihiro Yoshimura, Hisao Ogawa, Hirofumi Yasue
Format: Article
Language:English
Published: Wiley 2016-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
acute myocardial infarction
alcohol flushing syndrome
aldehyde dehydrogenase 2
coronary spasm
coronary spastic angina
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.003247

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.116.003247

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