Statistical analysis of single-copy assays when some observations are zero
Observational and interventional studies for HIV cure research often use single-copy assays to quantify rare entities in blood or tissue samples. Statistical analysis of such measurements presents challenges due to tissue sampling variability and frequent findings of 0 copies in the sample analysed....
Main Authors: | Peter Bacchetti, Ronald J. Bosch, Eileen P. Scully, Xutao Deng, Michael P. Busch, Steven G. Deeks, Sharon R. Lewin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
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Series: | Journal of Virus Eradication |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2055664020300479 |
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