Suicide Risk in Post-COVID-19 Syndrome

Post-acute sequelae of COVID-19 include several neuropsychiatric disorders. Little is known about the relationship between post-COVID-19 syndrome and suicidality. The aim of the study was to investigate the risk of suicide in subjects with persistent post-COVID-19 syndrome. One-thousand five-hundred...

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Main Authors: Alessio Simonetti, Evelina Bernardi, Delfina Janiri, Marianna Mazza, Silvia Montanari, Antonello Catinari, Beatrice Terenzi, Matteo Tosato, Vincenzo Galluzzo, Francesca Ciciarello, Francesco Landi, Gabriele Sani
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/12/12/2019
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author Alessio Simonetti
Evelina Bernardi
Delfina Janiri
Marianna Mazza
Silvia Montanari
Antonello Catinari
Beatrice Terenzi
Matteo Tosato
Vincenzo Galluzzo
Francesca Ciciarello
Francesco Landi
Gabriele Sani
author_facet Alessio Simonetti
Evelina Bernardi
Delfina Janiri
Marianna Mazza
Silvia Montanari
Antonello Catinari
Beatrice Terenzi
Matteo Tosato
Vincenzo Galluzzo
Francesca Ciciarello
Francesco Landi
Gabriele Sani
author_sort Alessio Simonetti
collection DOAJ
description Post-acute sequelae of COVID-19 include several neuropsychiatric disorders. Little is known about the relationship between post-COVID-19 syndrome and suicidality. The aim of the study was to investigate the risk of suicide in subjects with persistent post-COVID-19 syndrome. One-thousand five-hundred eighty-eight subjects were assessed in the Post-Acute Care Service at the Fondazione Policlinico Universitario “Agostino Gemelli” IRCCS of Rome. Assessment included: (a) sociodemographic characteristics; (b) symptoms during and after COVID-19; (c) psychopathological evaluation. Participants were divided in those with (SUI) or without (NON SUI) suicide risk according to the Mini International Neuropsychiatric Interview. Additionally, subjects with SUI were split into those with high (HIGH SUI) and low (LOW SUI) suicide risk. Between-group comparisons were made with <i>t</i>-tests for continuous variables and χ<sup>2</sup> tests for categorical variables. SUI showed greater percentages of physical complaints during and after COVID-19, greater percentages of psychiatric history and presence of psychiatric history in relatives, greater percentages of subjects previously undergoing psychopharmacotherapy, and greater levels of anxiety, mixed depressive symptoms, general psychopathology than NON SUI. HIGH SUI showed greater number of symptoms during and after COVID-19 and higher levels of mixed depressive symptoms than LOW SUI. Percentages of subjects undergoing psychotherapy was higher in LOW SUI than HIGH SUI. Greater levels of physical complaints and psychopathology during post-COVID-syndrome might enhance the risk of committing suicide. Treatment of physical complaints and psychotherapy might reduce suicide risk.
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spelling doaj.art-458b04c5d7bb438fa1778858386cc6e52023-11-24T16:02:14ZengMDPI AGJournal of Personalized Medicine2075-44262022-12-011212201910.3390/jpm12122019Suicide Risk in Post-COVID-19 SyndromeAlessio Simonetti0Evelina Bernardi1Delfina Janiri2Marianna Mazza3Silvia Montanari4Antonello Catinari5Beatrice Terenzi6Matteo Tosato7Vincenzo Galluzzo8Francesca Ciciarello9Francesco Landi10Gabriele Sani11Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USADepartment of Neuroscience, Section of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, ItalyMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USADepartment of Neuroscience, Section of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, ItalyDepartment of Neuroscience, Section of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, ItalyDepartment of Neuroscience, Section of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, ItalyDepartment of Neuroscience, Section of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, ItalyDepartment of Geriatrics, Università Cattolica del Sacro Cuore, 00168 Rome, ItalyDepartment of Geriatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyDepartment of Geriatrics, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyDepartment of Geriatrics, Università Cattolica del Sacro Cuore, 00168 Rome, ItalyDepartment of Neuroscience, Section of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, ItalyPost-acute sequelae of COVID-19 include several neuropsychiatric disorders. Little is known about the relationship between post-COVID-19 syndrome and suicidality. The aim of the study was to investigate the risk of suicide in subjects with persistent post-COVID-19 syndrome. One-thousand five-hundred eighty-eight subjects were assessed in the Post-Acute Care Service at the Fondazione Policlinico Universitario “Agostino Gemelli” IRCCS of Rome. Assessment included: (a) sociodemographic characteristics; (b) symptoms during and after COVID-19; (c) psychopathological evaluation. Participants were divided in those with (SUI) or without (NON SUI) suicide risk according to the Mini International Neuropsychiatric Interview. Additionally, subjects with SUI were split into those with high (HIGH SUI) and low (LOW SUI) suicide risk. Between-group comparisons were made with <i>t</i>-tests for continuous variables and χ<sup>2</sup> tests for categorical variables. SUI showed greater percentages of physical complaints during and after COVID-19, greater percentages of psychiatric history and presence of psychiatric history in relatives, greater percentages of subjects previously undergoing psychopharmacotherapy, and greater levels of anxiety, mixed depressive symptoms, general psychopathology than NON SUI. HIGH SUI showed greater number of symptoms during and after COVID-19 and higher levels of mixed depressive symptoms than LOW SUI. Percentages of subjects undergoing psychotherapy was higher in LOW SUI than HIGH SUI. Greater levels of physical complaints and psychopathology during post-COVID-syndrome might enhance the risk of committing suicide. Treatment of physical complaints and psychotherapy might reduce suicide risk.https://www.mdpi.com/2075-4426/12/12/2019suicidedepressionpsychopathologyCOVID-19post-COVID-19 syndrome
spellingShingle Alessio Simonetti
Evelina Bernardi
Delfina Janiri
Marianna Mazza
Silvia Montanari
Antonello Catinari
Beatrice Terenzi
Matteo Tosato
Vincenzo Galluzzo
Francesca Ciciarello
Francesco Landi
Gabriele Sani
Suicide Risk in Post-COVID-19 Syndrome
Journal of Personalized Medicine
suicide
depression
psychopathology
COVID-19
post-COVID-19 syndrome
title Suicide Risk in Post-COVID-19 Syndrome
title_full Suicide Risk in Post-COVID-19 Syndrome
title_fullStr Suicide Risk in Post-COVID-19 Syndrome
title_full_unstemmed Suicide Risk in Post-COVID-19 Syndrome
title_short Suicide Risk in Post-COVID-19 Syndrome
title_sort suicide risk in post covid 19 syndrome
topic suicide
depression
psychopathology
COVID-19
post-COVID-19 syndrome
url https://www.mdpi.com/2075-4426/12/12/2019
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