Engineering Abiotic Stress Tolerance in Crop Plants through CRISPR Genome Editing
Environmental abiotic stresses challenge food security by depressing crop yields often exceeding 50% of their annual production. Different methods, including conventional as well as genomic-assisted breeding, mutagenesis, and genetic engineering have been utilized to enhance stress resilience in sev...
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MDPI AG
2022-11-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/11/22/3590 |
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| author | Mehboob-ur Rahman Sana Zulfiqar Muhammad Ahmad Raza Niaz Ahmad Baohong Zhang |
| author_facet | Mehboob-ur Rahman Sana Zulfiqar Muhammad Ahmad Raza Niaz Ahmad Baohong Zhang |
| author_sort | Mehboob-ur Rahman |
| collection | DOAJ |
| description | Environmental abiotic stresses challenge food security by depressing crop yields often exceeding 50% of their annual production. Different methods, including conventional as well as genomic-assisted breeding, mutagenesis, and genetic engineering have been utilized to enhance stress resilience in several crop species. Plant breeding has been partly successful in developing crop varieties against abiotic stresses owning to the complex genetics of the traits as well as the narrow genetic base in the germplasm. Irrespective of the fact that genetic engineering can transfer gene(s) from any organism(s), transgenic crops have become controversial mainly due to the potential risk of transgene-outcrossing. Consequently, the cultivation of transgenic crops is banned in certain countries, particularly in European countries. In this scenario, the discovery of the CRISPR tool provides a platform for producing transgene-free genetically edited plants—similar to the mutagenized crops that are not extensively regulated such as genetically modified organisms (GMOs). Thus, the genome-edited plants without a transgene would likely go into the field without any restriction. Here, we focused on the deployment of CRISPR for the successful development of abiotic stress-tolerant crop plants for sustaining crop productivity under changing environments. |
| first_indexed | 2024-03-09T18:25:16Z |
| format | Article |
| id | doaj.art-458cfc5d8c4e464383663508e82173d9 |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-09T18:25:16Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
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| series | Cells |
| spelling | doaj.art-458cfc5d8c4e464383663508e82173d92023-11-24T07:57:53ZengMDPI AGCells2073-44092022-11-011122359010.3390/cells11223590Engineering Abiotic Stress Tolerance in Crop Plants through CRISPR Genome EditingMehboob-ur Rahman0Sana Zulfiqar1Muhammad Ahmad Raza2Niaz Ahmad3Baohong Zhang4Plant Genomics and Molecular Breeding Laboratory, National Institute for Biotechnology and Genetic Engineering College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad 38000, PakistanPlant Genomics and Molecular Breeding Laboratory, National Institute for Biotechnology and Genetic Engineering College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad 38000, PakistanPlant Genomics and Molecular Breeding Laboratory, National Institute for Biotechnology and Genetic Engineering College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad 38000, PakistanPlant Genomics and Molecular Breeding Laboratory, National Institute for Biotechnology and Genetic Engineering College, Pakistan Institute of Engineering and Applied Sciences (NIBGE-C, PIEAS), Faisalabad 38000, PakistanDepartment of Biology, East Carolina University, Greenville, NC 27858, USAEnvironmental abiotic stresses challenge food security by depressing crop yields often exceeding 50% of their annual production. Different methods, including conventional as well as genomic-assisted breeding, mutagenesis, and genetic engineering have been utilized to enhance stress resilience in several crop species. Plant breeding has been partly successful in developing crop varieties against abiotic stresses owning to the complex genetics of the traits as well as the narrow genetic base in the germplasm. Irrespective of the fact that genetic engineering can transfer gene(s) from any organism(s), transgenic crops have become controversial mainly due to the potential risk of transgene-outcrossing. Consequently, the cultivation of transgenic crops is banned in certain countries, particularly in European countries. In this scenario, the discovery of the CRISPR tool provides a platform for producing transgene-free genetically edited plants—similar to the mutagenized crops that are not extensively regulated such as genetically modified organisms (GMOs). Thus, the genome-edited plants without a transgene would likely go into the field without any restriction. Here, we focused on the deployment of CRISPR for the successful development of abiotic stress-tolerant crop plants for sustaining crop productivity under changing environments.https://www.mdpi.com/2073-4409/11/22/3590CRISPRdroughtsalinityheatheavy metalsfield crops |
| spellingShingle | Mehboob-ur Rahman Sana Zulfiqar Muhammad Ahmad Raza Niaz Ahmad Baohong Zhang Engineering Abiotic Stress Tolerance in Crop Plants through CRISPR Genome Editing Cells CRISPR drought salinity heat heavy metals field crops |
| title | Engineering Abiotic Stress Tolerance in Crop Plants through CRISPR Genome Editing |
| title_full | Engineering Abiotic Stress Tolerance in Crop Plants through CRISPR Genome Editing |
| title_fullStr | Engineering Abiotic Stress Tolerance in Crop Plants through CRISPR Genome Editing |
| title_full_unstemmed | Engineering Abiotic Stress Tolerance in Crop Plants through CRISPR Genome Editing |
| title_short | Engineering Abiotic Stress Tolerance in Crop Plants through CRISPR Genome Editing |
| title_sort | engineering abiotic stress tolerance in crop plants through crispr genome editing |
| topic | CRISPR drought salinity heat heavy metals field crops |
| url | https://www.mdpi.com/2073-4409/11/22/3590 |
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