Molecular docking and anti-ulcerative potential of Cucumis (L. Inodorous) on ibuprofen induced gastric ulceration in male wistar animals

Molecular docking and anti-ulcerative potential of Cucumis (L. Inodorous) on ibuprofen induced gastric ulceration in male wistar animals

Background: The use of NSAIDs have caused stomach injury by inhibiting endogenous mucosal prostaglandin production. Cucumis melo is reported to possess antiulcer potential. This study investigates the mechanism underlying the antiulcer potentials of Cucumis melo (CUM). Methods: Thirty-five male Wist...

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Bibliographic Details
Main Authors: Grace Adebayo-Gege, Zainab Shehu Uthman, Moses Dele Adams, Tarfa Florence, Danazumi Umar Haruna, Ngabea Murtala Audu, Hamidu Jabba Lawan, Ozegbe Queen, Onwuchekwa Chinedu, Ajibola Meraiyebu, Ojo Kafaru
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Cucumis melo
Ibuprofen
Gastric ulcer
Prostaglandin E2 receptor
Folic acid
Delta7-avenasterol
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223003190

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