Physiological and Hormonal Effects of Titanium Dioxide Nanoparticles on Thyroid Function and the Impact on Bodyweight in Male Rats
Fifty-four Sprague-Dawley albino adult male rats were classified into three main groups each of 18 rats treated for a particular duration (1,2, and 4) weeks respectively. Each group was subdivided into three subgroups each of six rats treated as follows; group (1) serve as normal control, group (2,...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Arabic |
| Published: |
College of Science for Women, University of Baghdad
2023-04-01
|
| Series: | Baghdad Science Journal |
| Subjects: | |
| Online Access: | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/3683 |
| _version_ | 1797854391716282368 |
|---|---|
| author | Noori Mohammed Luaibi Raghda Ali Mohammed |
| author_facet | Noori Mohammed Luaibi Raghda Ali Mohammed |
| author_sort | Noori Mohammed Luaibi |
| collection | DOAJ |
| description |
Fifty-four Sprague-Dawley albino adult male rats were classified into three main groups each of 18 rats treated for a particular duration (1,2, and 4) weeks respectively. Each group was subdivided into three subgroups each of six rats treated as follows; group (1) serve as normal control, group (2, and 3) intra-peritoneal treated with TiO2NPs (50,200) mg/kg respectively, body *weight of all rats was measured before and after the experiment, then rats were dissected at the end of each experiment and the weights of the thyroid was measured. The result showed a highly significant decrease (p<0.01) in thyroid gland weight, a highly significant increase (p<0.01) in body weights and TSH, while a highly significant decrease (p<0.01) inT3 and T4 was observed in all different doses (50,200) mg/kg at durations 1,2 and 4 weeks. So, this study confirms body weight gain is associated with thyroid dysfunction.
|
| first_indexed | 2024-04-09T20:06:20Z |
| format | Article |
| id | doaj.art-458f4937e0764357807b48d720eb35d3 |
| institution | Directory Open Access Journal |
| issn | 2078-8665 2411-7986 |
| language | Arabic |
| last_indexed | 2024-04-09T20:06:20Z |
| publishDate | 2023-04-01 |
| publisher | College of Science for Women, University of Baghdad |
| record_format | Article |
| series | Baghdad Science Journal |
| spelling | doaj.art-458f4937e0764357807b48d720eb35d32023-04-01T19:39:52ZaraCollege of Science for Women, University of BaghdadBaghdad Science Journal2078-86652411-79862023-04-0120210.21123/bsj.2022.3683Physiological and Hormonal Effects of Titanium Dioxide Nanoparticles on Thyroid Function and the Impact on Bodyweight in Male RatsNoori Mohammed Luaibi0Raghda Ali Mohammed1Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq.Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq. Fifty-four Sprague-Dawley albino adult male rats were classified into three main groups each of 18 rats treated for a particular duration (1,2, and 4) weeks respectively. Each group was subdivided into three subgroups each of six rats treated as follows; group (1) serve as normal control, group (2, and 3) intra-peritoneal treated with TiO2NPs (50,200) mg/kg respectively, body *weight of all rats was measured before and after the experiment, then rats were dissected at the end of each experiment and the weights of the thyroid was measured. The result showed a highly significant decrease (p<0.01) in thyroid gland weight, a highly significant increase (p<0.01) in body weights and TSH, while a highly significant decrease (p<0.01) inT3 and T4 was observed in all different doses (50,200) mg/kg at durations 1,2 and 4 weeks. So, this study confirms body weight gain is associated with thyroid dysfunction. https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/3683Body weight, Nanoparticle, Rats, Thyroid gland, TiO2NPs |
| spellingShingle | Noori Mohammed Luaibi Raghda Ali Mohammed Physiological and Hormonal Effects of Titanium Dioxide Nanoparticles on Thyroid Function and the Impact on Bodyweight in Male Rats Baghdad Science Journal Body weight, Nanoparticle, Rats, Thyroid gland, TiO2NPs |
| title | Physiological and Hormonal Effects of Titanium Dioxide Nanoparticles on Thyroid Function and the Impact on Bodyweight in Male Rats |
| title_full | Physiological and Hormonal Effects of Titanium Dioxide Nanoparticles on Thyroid Function and the Impact on Bodyweight in Male Rats |
| title_fullStr | Physiological and Hormonal Effects of Titanium Dioxide Nanoparticles on Thyroid Function and the Impact on Bodyweight in Male Rats |
| title_full_unstemmed | Physiological and Hormonal Effects of Titanium Dioxide Nanoparticles on Thyroid Function and the Impact on Bodyweight in Male Rats |
| title_short | Physiological and Hormonal Effects of Titanium Dioxide Nanoparticles on Thyroid Function and the Impact on Bodyweight in Male Rats |
| title_sort | physiological and hormonal effects of titanium dioxide nanoparticles on thyroid function and the impact on bodyweight in male rats |
| topic | Body weight, Nanoparticle, Rats, Thyroid gland, TiO2NPs |
| url | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/3683 |
| work_keys_str_mv | AT noorimohammedluaibi physiologicalandhormonaleffectsoftitaniumdioxidenanoparticlesonthyroidfunctionandtheimpactonbodyweightinmalerats AT raghdaalimohammed physiologicalandhormonaleffectsoftitaniumdioxidenanoparticlesonthyroidfunctionandtheimpactonbodyweightinmalerats |