Plasma cell dynamics in the bone marrow niche

Plasma cell dynamics in the bone marrow niche

Summary: Using intravital imaging, we report that bone marrow (BM) plasma cells (PCs) are motile. BM PCs exhibit a unique migration pattern, characterized by intermittent periods of high motility and longer stretches of confined migration or arrest. BM PCs accumulate into clusters, which have reduce...

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Bibliographic Details
Main Authors: Zachary Benet, Zhixin Jing, David R. Fooksman
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Cell Reports
Subjects:
plasma cells
bone marrow
intravital imaging
migration
CXCR4
APRIL
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721000462

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