Whole genome sequencing reveals complexity in both HPV sequences present and HPV integrations in HPV-positive oropharyngeal squamous cell carcinomas

Whole genome sequencing reveals complexity in both HPV sequences present and HPV integrations in HPV-positive oropharyngeal squamous cell carcinomas

Abstract Background High risk human papillomaviruses (HPV) plays important roles in the development of cervical cancer, a number of other anogenital cancer and they are increasingly found in oropharyngeal squamous cell carcinoma (OPSCC), however there has not been comprehensive analysis about the ro...

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Bibliographic Details
Main Authors: Ge Gao, Jintu Wang, Jan L. Kasperbauer, Nicole M. Tombers, Fei Teng, Honglan Gou, Yonggang Zhao, Zhenhong Bao, David I. Smith
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Cancer
Subjects:
Next generation sequencing
Whole genome sequencing
HPV
OPSCC
HPV integration
Online Access:http://link.springer.com/article/10.1186/s12885-019-5536-1

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