The Impact on Infectivity and Neutralization Efficiency of SARS-CoV-2 Lineage B.1.351 Pseudovirus

The Impact on Infectivity and Neutralization Efficiency of SARS-CoV-2 Lineage B.1.351 Pseudovirus

A new variant of SARS-CoV-2 B.1.351 lineage (first found in South Africa) has been raising global concern due to its harboring of multiple mutations in the spike that potentially increase transmissibility and yield resistance to neutralizing antibodies. We here tested infectivity and neutralization...

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Bibliographic Details
Main Authors: Yeong Jun Kim, Ui Soon Jang, Sandrine M. Soh, Joo-Youn Lee, Hye-Ra Lee
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Viruses
Subjects:
SARS-CoV-2
B.1.351
K417N and E484K mutation of spike
viral infectivity
neutralization
Casirivimab
Online Access:https://www.mdpi.com/1999-4915/13/4/633

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