mRNA-LNP vaccination-based immunotherapy augments CD8+ T cell responses against HPV-positive oropharyngeal cancer

mRNA-LNP vaccination-based immunotherapy augments CD8+ T cell responses against HPV-positive oropharyngeal cancer

Abstract Although mRNA vaccines are known as potent activators of antigen-specific immune responses against infectious diseases, limited understanding of how they drive the functional commitment of CD8+ T cells in tumor microenvironment (TME) and secondary lymphoid organs hinders their broader appli...

Full description

Bibliographic Details
Main Authors: Ke Qiu, Xing Duan, Minzi Mao, Yao Song, Yufang Rao, Danni Cheng, Lan Feng, Xiuli Shao, Chuanhuan Jiang, Hai Huang, Yan Wang, Huifang Li, Xuemei Chen, Sisi Wu, Dan Luo, Fei Chen, Xingchen Peng, Yongbo Zheng, Haiyang Wang, Jun Liu, Yu Zhao, Xiangrong Song, Jianjun Ren
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00733-8

Internet

https://doi.org/10.1038/s41541-023-00733-8

Similar Items