Assessment of mumps-containing vaccine effectiveness by dose during 2006 to 2020 in Quzhou, China
Mumps cases were reported frequently when a routine dose measles–mumps–rubella(MMR) achieved high coverage in Quzhou. The supplementary immunization activities (SIA) using measles mumps (MM) was conducted to control mumps outbreaks. The effectiveness of one and two doses of mumps-containing vaccine...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-11-01
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| Series: | Human Vaccines & Immunotherapeutics |
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| Online Access: | http://dx.doi.org/10.1080/21645515.2022.2086774 |
| _version_ | 1797673192623439872 |
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| author | Zhiying Yin Tingcui Wen Quanjun Fang Canjie Zheng Xiaoying Gong Junji Li Shuangqing Wang Ziling Xiang |
| author_facet | Zhiying Yin Tingcui Wen Quanjun Fang Canjie Zheng Xiaoying Gong Junji Li Shuangqing Wang Ziling Xiang |
| author_sort | Zhiying Yin |
| collection | DOAJ |
| description | Mumps cases were reported frequently when a routine dose measles–mumps–rubella(MMR) achieved high coverage in Quzhou. The supplementary immunization activities (SIA) using measles mumps (MM) was conducted to control mumps outbreaks. The effectiveness of one and two doses of mumps-containing vaccine (MuCV) was assessed using surveillance data in this study. Mumps cases and immunization information were retrieved from the National Notifiable Disease Reporting System (NNDRS) and the Zhejiang Provincial Immunization Information System (ZJIIS), respectively. Mumps cases of children born from 2006 to 2010 were included. Vaccine effectiveness by dose was calculated using the screening method. A total of 956 mumps cases were identified, of whom 754 (78.9%) had received one dose of MuCV; 108 (11.3%) had received two doses; 94 (9.8%) were unvaccinated. The coverage of one-dose MuCV in the 2006–2010 birth cohorts ranged from 91.6% to 98.9%. Except the 2009 birth cohort in which the coverage of two doses of MuCV was 55.1%, the others were less than 10%. Vaccine effectiveness (VE) of one dose ranged from 47.4% to 86.0%, while VE of two doses ranged from 64.0% to 92.4%. The VE of one and two doses of MuCV waned over time, but the VE of two doses was consistently higher than that of one dose in the same period. The vaccine schedule with two-dose MMR should be implemented among children in Quzhou. The optimal age for the second dose needs to be further evaluated. |
| first_indexed | 2024-03-11T21:40:33Z |
| format | Article |
| id | doaj.art-45a63612317846689b22d666be092403 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T21:40:33Z |
| publishDate | 2022-11-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-45a63612317846689b22d666be0924032023-09-26T13:19:07ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2022-11-0118510.1080/21645515.2022.20867742086774Assessment of mumps-containing vaccine effectiveness by dose during 2006 to 2020 in Quzhou, ChinaZhiying Yin0Tingcui Wen1Quanjun Fang2Canjie Zheng3Xiaoying Gong4Junji Li5Shuangqing Wang6Ziling Xiang7Quzhou Center for Disease Control and PreventionZhejiang Chinese Medical UniversityQuzhou Center for Disease Control and PreventionQuzhou Center for Disease Control and PreventionQuzhou Center for Disease Control and PreventionQuzhou Center for Disease Control and PreventionQuzhou Center for Disease Control and PreventionQuzhou Center for Disease Control and PreventionMumps cases were reported frequently when a routine dose measles–mumps–rubella(MMR) achieved high coverage in Quzhou. The supplementary immunization activities (SIA) using measles mumps (MM) was conducted to control mumps outbreaks. The effectiveness of one and two doses of mumps-containing vaccine (MuCV) was assessed using surveillance data in this study. Mumps cases and immunization information were retrieved from the National Notifiable Disease Reporting System (NNDRS) and the Zhejiang Provincial Immunization Information System (ZJIIS), respectively. Mumps cases of children born from 2006 to 2010 were included. Vaccine effectiveness by dose was calculated using the screening method. A total of 956 mumps cases were identified, of whom 754 (78.9%) had received one dose of MuCV; 108 (11.3%) had received two doses; 94 (9.8%) were unvaccinated. The coverage of one-dose MuCV in the 2006–2010 birth cohorts ranged from 91.6% to 98.9%. Except the 2009 birth cohort in which the coverage of two doses of MuCV was 55.1%, the others were less than 10%. Vaccine effectiveness (VE) of one dose ranged from 47.4% to 86.0%, while VE of two doses ranged from 64.0% to 92.4%. The VE of one and two doses of MuCV waned over time, but the VE of two doses was consistently higher than that of one dose in the same period. The vaccine schedule with two-dose MMR should be implemented among children in Quzhou. The optimal age for the second dose needs to be further evaluated.http://dx.doi.org/10.1080/21645515.2022.2086774mumpsmumps-containing vaccinevaccine effectiveness |
| spellingShingle | Zhiying Yin Tingcui Wen Quanjun Fang Canjie Zheng Xiaoying Gong Junji Li Shuangqing Wang Ziling Xiang Assessment of mumps-containing vaccine effectiveness by dose during 2006 to 2020 in Quzhou, China Human Vaccines & Immunotherapeutics mumps mumps-containing vaccine vaccine effectiveness |
| title | Assessment of mumps-containing vaccine effectiveness by dose during 2006 to 2020 in Quzhou, China |
| title_full | Assessment of mumps-containing vaccine effectiveness by dose during 2006 to 2020 in Quzhou, China |
| title_fullStr | Assessment of mumps-containing vaccine effectiveness by dose during 2006 to 2020 in Quzhou, China |
| title_full_unstemmed | Assessment of mumps-containing vaccine effectiveness by dose during 2006 to 2020 in Quzhou, China |
| title_short | Assessment of mumps-containing vaccine effectiveness by dose during 2006 to 2020 in Quzhou, China |
| title_sort | assessment of mumps containing vaccine effectiveness by dose during 2006 to 2020 in quzhou china |
| topic | mumps mumps-containing vaccine vaccine effectiveness |
| url | http://dx.doi.org/10.1080/21645515.2022.2086774 |
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