Expression of Syndecan 1 on Periodontium treated with Topical Application of Aloe-Vera

Background: Periodontium mainly exposed to injury by trauma or pathologic diseases, Aloe vera is a plant has many basic ingredients in its extracted gel that acts as wound healing accelerator in addition to that it's safe, and economical and without recordable of side effect. This study aimed i...

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Main Authors: Sabrin Sami Abed, Athra'a Y. Al-Hijazi
Format: Article
Language:English
Published: College of Dentistry/ University of Baghdad 2016-09-01
Series:Journal of Baghdad College of Dentistry
Online Access:https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/1430
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author Sabrin Sami Abed
Athra'a Y. Al-Hijazi
author_facet Sabrin Sami Abed
Athra'a Y. Al-Hijazi
author_sort Sabrin Sami Abed
collection DOAJ
description Background: Periodontium mainly exposed to injury by trauma or pathologic diseases, Aloe vera is a plant has many basic ingredients in its extracted gel that acts as wound healing accelerator in addition to that it's safe, and economical and without recordable of side effect. This study aimed is to evaluate the effect of topical application of Aloe vera on expression of syndecan -1 by periodontium tissue. Materials and methods: Thirty six male Albino rats were subjected for periodontium defect by electric scaler on the distal sides of both lower anterior teeth. The animals divided into two groups; control group (without treatment) and the experimental group treated with 1µLAloe vera gel/normal saline. Periodontal healing was examined at periods (3, 7, 14 days) for immunohistochemical localization of syndecan 1. Results: Immunohistochemical examination of this study revealed that the aloe vera treatment increase expression of syndecan 1 by epithelial cell, osteoblasts, fibroblast, stromal cells and with highly significant differences in comparison with control and saline. Conclusion: Aloe vera gel may affect the expression of syndecan 1 which seems to play a role in periodontium healing.
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spelling doaj.art-45a6c2a5febb48ef8085842cb9f998dc2022-12-22T04:17:48ZengCollege of Dentistry/ University of BaghdadJournal of Baghdad College of Dentistry2311-52702016-09-0128310.12816/0031129Expression of Syndecan 1 on Periodontium treated with Topical Application of Aloe-VeraSabrin Sami AbedAthra'a Y. Al-HijaziBackground: Periodontium mainly exposed to injury by trauma or pathologic diseases, Aloe vera is a plant has many basic ingredients in its extracted gel that acts as wound healing accelerator in addition to that it's safe, and economical and without recordable of side effect. This study aimed is to evaluate the effect of topical application of Aloe vera on expression of syndecan -1 by periodontium tissue. Materials and methods: Thirty six male Albino rats were subjected for periodontium defect by electric scaler on the distal sides of both lower anterior teeth. The animals divided into two groups; control group (without treatment) and the experimental group treated with 1µLAloe vera gel/normal saline. Periodontal healing was examined at periods (3, 7, 14 days) for immunohistochemical localization of syndecan 1. Results: Immunohistochemical examination of this study revealed that the aloe vera treatment increase expression of syndecan 1 by epithelial cell, osteoblasts, fibroblast, stromal cells and with highly significant differences in comparison with control and saline. Conclusion: Aloe vera gel may affect the expression of syndecan 1 which seems to play a role in periodontium healing.https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/1430
spellingShingle Sabrin Sami Abed
Athra'a Y. Al-Hijazi
Expression of Syndecan 1 on Periodontium treated with Topical Application of Aloe-Vera
Journal of Baghdad College of Dentistry
title Expression of Syndecan 1 on Periodontium treated with Topical Application of Aloe-Vera
title_full Expression of Syndecan 1 on Periodontium treated with Topical Application of Aloe-Vera
title_fullStr Expression of Syndecan 1 on Periodontium treated with Topical Application of Aloe-Vera
title_full_unstemmed Expression of Syndecan 1 on Periodontium treated with Topical Application of Aloe-Vera
title_short Expression of Syndecan 1 on Periodontium treated with Topical Application of Aloe-Vera
title_sort expression of syndecan 1 on periodontium treated with topical application of aloe vera
url https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/1430
work_keys_str_mv AT sabrinsamiabed expressionofsyndecan1onperiodontiumtreatedwithtopicalapplicationofaloevera
AT athraayalhijazi expressionofsyndecan1onperiodontiumtreatedwithtopicalapplicationofaloevera