The role of distinct co-mutation patterns with TP53 mutation in immunotherapy for NSCLC

The role of distinct co-mutation patterns with TP53 mutation in immunotherapy for NSCLC

TP53 mutations was reported to be correlated to the efficacy of program death-1 (PD-1) and program death ligand-1 (PD-L1). The role of co-mutations of TP53 with other recurrently mutated genes in outcome of anti-PD-(L)1 treatment for non-small cell lung cancer (NSCLC) is unknown. Here we mined a pre...

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Bibliographic Details
Main Authors: Shuhang Wang, Miaomiao Jiang, Zuozhen Yang, Xiaoyun Huang, Ning Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-01-01
Series:Genes and Diseases
Subjects:
NSCLC
PD-1
PD-L1
PFS
TP53 co-mutation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220300532

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