Therapeutic angiogenesis for cardiovascular disease
<p>Abstract</p> <p>The identification of angiogenic growth factors, such as vascular endothelial growth factor and fibroblast growth factor, has fueled interest in using such factors to induce therapeutic angiogenesis. The results of numerous animal studies and clinical trials have...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2001-10-01
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| Series: | Current Controlled Trials in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1186/cvm-2-6-278 |
| _version_ | 1818482784069484544 |
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| author | D'Amore Patricia A Ng Yin-Shan |
| author_facet | D'Amore Patricia A Ng Yin-Shan |
| author_sort | D'Amore Patricia A |
| collection | DOAJ |
| description | <p>Abstract</p> <p>The identification of angiogenic growth factors, such as vascular endothelial growth factor and fibroblast growth factor, has fueled interest in using such factors to induce therapeutic angiogenesis. The results of numerous animal studies and clinical trials have offered promise for new treatment strategies for various ischemic diseases. Increased understanding of the cellular and molecular biology of vessel growth has, however, prompted investigators and clinicians alike to reconsider the complexity of therapeutic angiogenesis. The realization that formation of a stable vessel is a complex, multistep process may provide useful insights into the design of the next generation of angiogenesis therapy.</p> |
| first_indexed | 2024-12-10T11:51:33Z |
| format | Article |
| id | doaj.art-45aa073cbb26470aab4d516c39ffbd0f |
| institution | Directory Open Access Journal |
| issn | 1468-6708 |
| language | English |
| last_indexed | 2024-12-10T11:51:33Z |
| publishDate | 2001-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Current Controlled Trials in Cardiovascular Medicine |
| spelling | doaj.art-45aa073cbb26470aab4d516c39ffbd0f2022-12-22T01:49:55ZengBMCCurrent Controlled Trials in Cardiovascular Medicine1468-67082001-10-012627828510.1186/cvm-2-6-278Therapeutic angiogenesis for cardiovascular diseaseD'Amore Patricia ANg Yin-Shan<p>Abstract</p> <p>The identification of angiogenic growth factors, such as vascular endothelial growth factor and fibroblast growth factor, has fueled interest in using such factors to induce therapeutic angiogenesis. The results of numerous animal studies and clinical trials have offered promise for new treatment strategies for various ischemic diseases. Increased understanding of the cellular and molecular biology of vessel growth has, however, prompted investigators and clinicians alike to reconsider the complexity of therapeutic angiogenesis. The realization that formation of a stable vessel is a complex, multistep process may provide useful insights into the design of the next generation of angiogenesis therapy.</p>http://dx.doi.org/10.1186/cvm-2-6-278collateralendothelial cellsischemianeovascularizationvascular endothelial growth factor |
| spellingShingle | D'Amore Patricia A Ng Yin-Shan Therapeutic angiogenesis for cardiovascular disease Current Controlled Trials in Cardiovascular Medicine collateral endothelial cells ischemia neovascularization vascular endothelial growth factor |
| title | Therapeutic angiogenesis for cardiovascular disease |
| title_full | Therapeutic angiogenesis for cardiovascular disease |
| title_fullStr | Therapeutic angiogenesis for cardiovascular disease |
| title_full_unstemmed | Therapeutic angiogenesis for cardiovascular disease |
| title_short | Therapeutic angiogenesis for cardiovascular disease |
| title_sort | therapeutic angiogenesis for cardiovascular disease |
| topic | collateral endothelial cells ischemia neovascularization vascular endothelial growth factor |
| url | http://dx.doi.org/10.1186/cvm-2-6-278 |
| work_keys_str_mv | AT damorepatriciaa therapeuticangiogenesisforcardiovasculardisease AT ngyinshan therapeuticangiogenesisforcardiovasculardisease |