Ubiquitin protein E3 ligase ASB9 suppresses proliferation and promotes apoptosis in human spermatogonial stem cell line by inducing HIF1AN degradation
Abstract Background Spermatogonial stem cells (SSCs) are critical for sustaining spermatogenesis. Even though several regulators of SSC have been identified in rodents, the regulatory mechanism of SSC in humans has yet to be discovered. Methods To explore the regulatory mechanisms of human SSCs, we...
Main Authors: | Ning Li, Qianyin Zhou, Zhang Yi, Huan Zhang, Dai Zhou |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-01-01
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Series: | Biological Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40659-023-00413-w |
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