Original research. Regional Wall Motion Abnormalities and Ventricular Function in Acute Peri-Myocarditis
Introduction: Myocardial involvement in pericardial diseases and the effect of pericardial inflammation and effusion on the function of the left ventricle (LV) is still a controversial issue. The present study aimed to evaluate LV regional wall abnormalities in patients with acute peri-myocarditis,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2017-03-01
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| Series: | Journal of Cardiovascular Emergencies |
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| Online Access: | https://doi.org/10.1515/jce-2017-0004 |
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| author | Matei Claudia Mester András Cernica Daniel Hodas Roxana Bordi Lehel |
| author_facet | Matei Claudia Mester András Cernica Daniel Hodas Roxana Bordi Lehel |
| author_sort | Matei Claudia |
| collection | DOAJ |
| description | Introduction: Myocardial involvement in pericardial diseases and the effect of pericardial inflammation and effusion on the function of the left ventricle (LV) is still a controversial issue. The present study aimed to evaluate LV regional wall abnormalities in patients with acute peri-myocarditis, using 3D echocardiographic assessment of LV contractility. Material and methods: The study included 56 subjects divided into two groups: Group 1 - 28 subjects with acute peri-myocarditis and Group 2 - 28 healthy controls. All subjects underwent a complete clinical examination, including laboratory tests. 3D echocardiography was performed to assess the left ventricular end-diastolic (EDV) and end-systolic volumes (ESV), and to calculate specific indexes for global and regional ventricular contractility, such as the index of contraction amplitude (ICA) and the regional index of contraction amplitude (RICA) for each segment corresponding to the region affected by peri- myocarditis. Results: 3D echocardiography showed no differences between the groups regarding the EDV (p = 0.2), the LV ejection fraction (Group 1: 55.82% ± 3.36% vs. Group 2: 57.21% ± 4.69%, p = 0.2). The ESV however, was significantly higher in Group 1 compared to Group 2 (55.78 ± 5.45 ml vs. 52.20 ± 6.43 ml, p = 0.04). ICA was similar between the groups (p = 0.2). However, the RICA was significantly lower in Group 1 compared to Group 2 (2.27 ± 0.63 vs. 5.16 ± 0.54, p <0.0001). Conclusions: The extension of the inflammatory process from the pericardium to the adjacent myocardial layer may affect the contractility of the LV. A good association exists between peri-myocarditis and the regional contractility abnormalities of the LV. |
| first_indexed | 2024-12-14T05:42:38Z |
| format | Article |
| id | doaj.art-45af7fbe07324d93bd914fcd7e2fb2e1 |
| institution | Directory Open Access Journal |
| issn | 2457-5518 |
| language | English |
| last_indexed | 2024-12-14T05:42:38Z |
| publishDate | 2017-03-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Cardiovascular Emergencies |
| spelling | doaj.art-45af7fbe07324d93bd914fcd7e2fb2e12022-12-21T23:14:59ZengSciendoJournal of Cardiovascular Emergencies2457-55182017-03-0131303510.1515/jce-2017-0004Original research. Regional Wall Motion Abnormalities and Ventricular Function in Acute Peri-MyocarditisMatei Claudia0Mester András1Cernica Daniel2Hodas Roxana3Bordi Lehel4“Dr. C-tin Opriș” County Emergency Clinical Hospital, Baia Mare, RomaniaCounty Emergency Clinical Hospital, Tîrgu Mureș, RomaniaCounty Emergency Clinical Hospital, Tîrgu Mureș, RomaniaCounty Emergency Clinical Hospital, Tîrgu Mureș, RomaniaCounty Emergency Clinical Hospital, Tîrgu Mureș, RomaniaIntroduction: Myocardial involvement in pericardial diseases and the effect of pericardial inflammation and effusion on the function of the left ventricle (LV) is still a controversial issue. The present study aimed to evaluate LV regional wall abnormalities in patients with acute peri-myocarditis, using 3D echocardiographic assessment of LV contractility. Material and methods: The study included 56 subjects divided into two groups: Group 1 - 28 subjects with acute peri-myocarditis and Group 2 - 28 healthy controls. All subjects underwent a complete clinical examination, including laboratory tests. 3D echocardiography was performed to assess the left ventricular end-diastolic (EDV) and end-systolic volumes (ESV), and to calculate specific indexes for global and regional ventricular contractility, such as the index of contraction amplitude (ICA) and the regional index of contraction amplitude (RICA) for each segment corresponding to the region affected by peri- myocarditis. Results: 3D echocardiography showed no differences between the groups regarding the EDV (p = 0.2), the LV ejection fraction (Group 1: 55.82% ± 3.36% vs. Group 2: 57.21% ± 4.69%, p = 0.2). The ESV however, was significantly higher in Group 1 compared to Group 2 (55.78 ± 5.45 ml vs. 52.20 ± 6.43 ml, p = 0.04). ICA was similar between the groups (p = 0.2). However, the RICA was significantly lower in Group 1 compared to Group 2 (2.27 ± 0.63 vs. 5.16 ± 0.54, p <0.0001). Conclusions: The extension of the inflammatory process from the pericardium to the adjacent myocardial layer may affect the contractility of the LV. A good association exists between peri-myocarditis and the regional contractility abnormalities of the LV.https://doi.org/10.1515/jce-2017-0004peri-myocarditisechocardiographyoriginal index of contractionamplitude |
| spellingShingle | Matei Claudia Mester András Cernica Daniel Hodas Roxana Bordi Lehel Original research. Regional Wall Motion Abnormalities and Ventricular Function in Acute Peri-Myocarditis Journal of Cardiovascular Emergencies peri-myocarditis echocardiography original index of contraction amplitude |
| title | Original research. Regional Wall Motion Abnormalities and Ventricular Function in Acute Peri-Myocarditis |
| title_full | Original research. Regional Wall Motion Abnormalities and Ventricular Function in Acute Peri-Myocarditis |
| title_fullStr | Original research. Regional Wall Motion Abnormalities and Ventricular Function in Acute Peri-Myocarditis |
| title_full_unstemmed | Original research. Regional Wall Motion Abnormalities and Ventricular Function in Acute Peri-Myocarditis |
| title_short | Original research. Regional Wall Motion Abnormalities and Ventricular Function in Acute Peri-Myocarditis |
| title_sort | original research regional wall motion abnormalities and ventricular function in acute peri myocarditis |
| topic | peri-myocarditis echocardiography original index of contraction amplitude |
| url | https://doi.org/10.1515/jce-2017-0004 |
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