Results of a prospective observational study of autologous peripheral blood mononuclear cell therapy for no-option critical limb-threatening ischemia and severe diabetic foot ulcers

Results of a prospective observational study of autologous peripheral blood mononuclear cell therapy for no-option critical limb-threatening ischemia and severe diabetic foot ulcers

Abstract Background Cell therapy with autologous peripheral blood mononuclear cells (PB-MNCs) may help restore limb perfusion in patients with diabetes mellitus and critical limb-threatening ischemia (CLTI) deemed not eligible for revascularization procedures and consequently at risk for major amput...

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Main Authors: Andrea Panunzi, Fabiana Madotto, Elena Sangalli, Federica Riccio, Adriana Barbara Sganzaroli, Paolo Galenda, Amelia Bertulessi, Maria Francesca Barmina, Ornella Ludovico, Orazio Fortunato, Francesco Setacci, Flavio Airoldi, Davide Tavano, Laura Giurato, Marco Meloni, Luigi Uccioli, Antonino Bruno, Gaia Spinetti, Carlo Maria Ferdinando Caravaggi
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cardiovascular Diabetology
Subjects:
Critical limb-threatening ischemia
Diabetes mellitus
Autologous cell therapy
Online Access:https://doi.org/10.1186/s12933-022-01629-y

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