Minced skin grafts for chronic wounds compared to conventional mesh grafts
Abstract Background and Aims Skin grafting is the single most effective method to close a chronic wound. The current standard of care is to use meshed split thickness skin grafts. This entails the use of surgical instruments that need to be autoclaved and to have a power source, which usually requir...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-06-01
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| Series: | Health Science Reports |
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| Online Access: | https://doi.org/10.1002/hsr2.1353 |
| _version_ | 1797791509301428224 |
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| author | Débora C. Sanches‐Pinto Elof Eriksson David S. Gomez Maria P. T. Nunes Rolf Gemperli Francisco G. Soriano |
| author_facet | Débora C. Sanches‐Pinto Elof Eriksson David S. Gomez Maria P. T. Nunes Rolf Gemperli Francisco G. Soriano |
| author_sort | Débora C. Sanches‐Pinto |
| collection | DOAJ |
| description | Abstract Background and Aims Skin grafting is the single most effective method to close a chronic wound. The current standard of care is to use meshed split thickness skin grafts. This entails the use of surgical instruments that need to be autoclaved and to have a power source, which usually requires an OR facility. The minced skin technique uses single use, presterilized instruments and the procedure can be done under local anesthesia, by a wound care practitioner, in a wound clinic, a physician's office or even at the bedside. The current study was designed to determine if the results from micrografting were non inferior to conventional mesh grafting. Methods In a prospective non inferiority study, 26 chronic ulcers were treated with micrografting (MSG) and 24 with conventional mesh grafts 1:3 (control group‐CG) in a total of 21 patients, 10 male and 11 female. The donor site areas in the MSG group were predetermined to 2.5 × 5 cm and the mesh grafts expansion was set at 1:3. Results In the first weeks postoperatively, micrograft healing initially lagged behind the conventional mesh grafts but at 60 days after grafting, all MSG wounds were healed. The MSG wounds had better pigmentation, less itching, and less scarring. The micrografting procedure was easy to learn and expeditious to perform. The MSG mean expansion was 9.1 compared to three times (CG). Conclusion The MSG procedure is not inferior to conventional mesh grafting, requires smaller donor sites, and can be done with single use instruments, under local anesthesia, with early discharge. |
| first_indexed | 2024-03-13T02:19:52Z |
| format | Article |
| id | doaj.art-45b20375ba9643a7af9c29217b1235ef |
| institution | Directory Open Access Journal |
| issn | 2398-8835 |
| language | English |
| last_indexed | 2024-03-13T02:19:52Z |
| publishDate | 2023-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj.art-45b20375ba9643a7af9c29217b1235ef2023-06-30T10:20:50ZengWileyHealth Science Reports2398-88352023-06-0166n/an/a10.1002/hsr2.1353Minced skin grafts for chronic wounds compared to conventional mesh graftsDébora C. Sanches‐Pinto0Elof Eriksson1David S. Gomez2Maria P. T. Nunes3Rolf Gemperli4Francisco G. Soriano5Divisão de Cirurgia Plástica e Queimaduras. Clinicas Hospital ‐ School of Medicine University of São Paulo São Paulo BrazilHarvard Medical School Boston Massachusetts USADivisão de Cirurgia Plástica e Queimaduras. Clinicas Hospital ‐ School of Medicine University of São Paulo São Paulo BrazilDepartment of Internal Medicine, School of Medicine University of São Paulo São Paulo BrazilDivisão de Cirurgia Plástica e Queimaduras. Clinicas Hospital ‐ School of Medicine University of São Paulo São Paulo BrazilSchool of Medicine University of São Paulo São Paulo BrazilAbstract Background and Aims Skin grafting is the single most effective method to close a chronic wound. The current standard of care is to use meshed split thickness skin grafts. This entails the use of surgical instruments that need to be autoclaved and to have a power source, which usually requires an OR facility. The minced skin technique uses single use, presterilized instruments and the procedure can be done under local anesthesia, by a wound care practitioner, in a wound clinic, a physician's office or even at the bedside. The current study was designed to determine if the results from micrografting were non inferior to conventional mesh grafting. Methods In a prospective non inferiority study, 26 chronic ulcers were treated with micrografting (MSG) and 24 with conventional mesh grafts 1:3 (control group‐CG) in a total of 21 patients, 10 male and 11 female. The donor site areas in the MSG group were predetermined to 2.5 × 5 cm and the mesh grafts expansion was set at 1:3. Results In the first weeks postoperatively, micrograft healing initially lagged behind the conventional mesh grafts but at 60 days after grafting, all MSG wounds were healed. The MSG wounds had better pigmentation, less itching, and less scarring. The micrografting procedure was easy to learn and expeditious to perform. The MSG mean expansion was 9.1 compared to three times (CG). Conclusion The MSG procedure is not inferior to conventional mesh grafting, requires smaller donor sites, and can be done with single use instruments, under local anesthesia, with early discharge.https://doi.org/10.1002/hsr2.1353burnschronic woundsmicrograftsskin graft expansionskin graftswound care |
| spellingShingle | Débora C. Sanches‐Pinto Elof Eriksson David S. Gomez Maria P. T. Nunes Rolf Gemperli Francisco G. Soriano Minced skin grafts for chronic wounds compared to conventional mesh grafts Health Science Reports burns chronic wounds micrografts skin graft expansion skin grafts wound care |
| title | Minced skin grafts for chronic wounds compared to conventional mesh grafts |
| title_full | Minced skin grafts for chronic wounds compared to conventional mesh grafts |
| title_fullStr | Minced skin grafts for chronic wounds compared to conventional mesh grafts |
| title_full_unstemmed | Minced skin grafts for chronic wounds compared to conventional mesh grafts |
| title_short | Minced skin grafts for chronic wounds compared to conventional mesh grafts |
| title_sort | minced skin grafts for chronic wounds compared to conventional mesh grafts |
| topic | burns chronic wounds micrografts skin graft expansion skin grafts wound care |
| url | https://doi.org/10.1002/hsr2.1353 |
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