Transforming Growth Factor-β Signaling in Fibrotic Diseases and Cancer-Associated Fibroblasts

Transforming Growth Factor-β Signaling in Fibrotic Diseases and Cancer-Associated Fibroblasts

Transforming growth factor-β (TGF-β) signaling is essential in embryo development and maintaining normal homeostasis. Extensive evidence shows that TGF-β activation acts on several cell types, including epithelial cells, fibroblasts, and immune cells, to form a pro-fibrotic environment, ultimately l...

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Bibliographic Details
Main Authors:	Xueke Shi, Christian D. Young, Hongmei Zhou, Xiao-Jing Wang
Format:	Article
Language:	English
Published:	MDPI AG 2020-12-01
Series:	Biomolecules
Subjects:	TGF-β signaling fibroblasts fibrotic diseases cancer cancer-associated fibroblast anti-fibrosis/cancer therapy
Online Access:	https://www.mdpi.com/2218-273X/10/12/1666

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