The current role of renal biopsy in the management of localized renal tumors

Introduction : In the current era of nephron-sparing surgery (NSS) for localized tumors, pretreatment tissue biopsy is being revisited and re-evaluated. Whether a renal biopsy can supplement imaging investigations to change patient management is a subject of current research. Materials and Method...

Full description

Bibliographic Details
Main Authors: Gagan Gautam, Kevin C Zorn
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-01-01
Series:Indian Journal of Urology
Subjects:
Online Access:http://www.indianjurol.com/article.asp?issn=0970-1591;year=2009;volume=25;issue=4;spage=494;epage=498;aulast=Gautam
_version_ 1818362127837036544
author Gagan Gautam
Kevin C Zorn
author_facet Gagan Gautam
Kevin C Zorn
author_sort Gagan Gautam
collection DOAJ
description Introduction : In the current era of nephron-sparing surgery (NSS) for localized tumors, pretreatment tissue biopsy is being revisited and re-evaluated. Whether a renal biopsy can supplement imaging investigations to change patient management is a subject of current research. Materials and Methods : We performed a database search in PubMed for manuscripts from 1988 to 2008 using the appropriate keywords. Manuscripts were selected according to their relevance to the current topic and incorporated into this review. Results : Preoperative renal biopsy has been utilized to effectively distinguish between benign and malignant tumors localized to the kidney with minimal additional morbidity attributable to the procedure. Tissue diagnosis can also potentially grade renal tumors and uncover unusual malignancies. Although its acceptance remains limited, with fear of false negative results, bleeding and tumor seeding, its ability to influence management decisions has been demonstrated in literature. Conclusions : The role of preoperative renal biopsy for localized renal tumors is likely to increase rapidly in the coming times. With the expanding scope and utilization of NSS, this diagnostic modality will find increased applicability and acceptance in individualizing management protocols in the future.
first_indexed 2024-12-13T21:27:39Z
format Article
id doaj.art-45b9f5f8755c46d68e676a7c698d8a50
institution Directory Open Access Journal
issn 0970-1591
1998-3824
language English
last_indexed 2024-12-13T21:27:39Z
publishDate 2009-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Urology
spelling doaj.art-45b9f5f8755c46d68e676a7c698d8a502022-12-21T23:30:54ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242009-01-0125449449810.4103/0970-1591.57926The current role of renal biopsy in the management of localized renal tumorsGagan GautamKevin C ZornIntroduction : In the current era of nephron-sparing surgery (NSS) for localized tumors, pretreatment tissue biopsy is being revisited and re-evaluated. Whether a renal biopsy can supplement imaging investigations to change patient management is a subject of current research. Materials and Methods : We performed a database search in PubMed for manuscripts from 1988 to 2008 using the appropriate keywords. Manuscripts were selected according to their relevance to the current topic and incorporated into this review. Results : Preoperative renal biopsy has been utilized to effectively distinguish between benign and malignant tumors localized to the kidney with minimal additional morbidity attributable to the procedure. Tissue diagnosis can also potentially grade renal tumors and uncover unusual malignancies. Although its acceptance remains limited, with fear of false negative results, bleeding and tumor seeding, its ability to influence management decisions has been demonstrated in literature. Conclusions : The role of preoperative renal biopsy for localized renal tumors is likely to increase rapidly in the coming times. With the expanding scope and utilization of NSS, this diagnostic modality will find increased applicability and acceptance in individualizing management protocols in the future.http://www.indianjurol.com/article.asp?issn=0970-1591;year=2009;volume=25;issue=4;spage=494;epage=498;aulast=GautamFine-needle aspiration cytologynephron-sparing surgeryrenal biopsyrenal tumorrenal cell carcinoma
spellingShingle Gagan Gautam
Kevin C Zorn
The current role of renal biopsy in the management of localized renal tumors
Indian Journal of Urology
Fine-needle aspiration cytology
nephron-sparing surgery
renal biopsy
renal tumor
renal cell carcinoma
title The current role of renal biopsy in the management of localized renal tumors
title_full The current role of renal biopsy in the management of localized renal tumors
title_fullStr The current role of renal biopsy in the management of localized renal tumors
title_full_unstemmed The current role of renal biopsy in the management of localized renal tumors
title_short The current role of renal biopsy in the management of localized renal tumors
title_sort current role of renal biopsy in the management of localized renal tumors
topic Fine-needle aspiration cytology
nephron-sparing surgery
renal biopsy
renal tumor
renal cell carcinoma
url http://www.indianjurol.com/article.asp?issn=0970-1591;year=2009;volume=25;issue=4;spage=494;epage=498;aulast=Gautam
work_keys_str_mv AT gagangautam thecurrentroleofrenalbiopsyinthemanagementoflocalizedrenaltumors
AT kevinczorn thecurrentroleofrenalbiopsyinthemanagementoflocalizedrenaltumors
AT gagangautam currentroleofrenalbiopsyinthemanagementoflocalizedrenaltumors
AT kevinczorn currentroleofrenalbiopsyinthemanagementoflocalizedrenaltumors