Gastric, Colonic, and Rectal Amyloidosis in the Setting of Familial Mediterranean Fever: A Unique Cause of Intractable Diarrhea

Familial Mediterranean fever (FMF) is a hereditary disorder characterized by episodes of fever, polyserositis, or cutaneous inflammation. The FMF attacks last 1–3 days and have no apparent triggers. Recurrent deposition of the serum amyloid A (SAA) protein in the gut can cause intractable diarrhea,...

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Main Authors: Lefika Bathobakae, Nida Ansari, Anas Mahmoud, Shayee Hasan, Ruhin Yuridullah, Sohail Qayyum, Sam Rae
Format: Article
Language:English
Published: Hindawi Limited 2024-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2024/6679725
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author Lefika Bathobakae
Nida Ansari
Anas Mahmoud
Shayee Hasan
Ruhin Yuridullah
Sohail Qayyum
Sam Rae
author_facet Lefika Bathobakae
Nida Ansari
Anas Mahmoud
Shayee Hasan
Ruhin Yuridullah
Sohail Qayyum
Sam Rae
author_sort Lefika Bathobakae
collection DOAJ
description Familial Mediterranean fever (FMF) is a hereditary disorder characterized by episodes of fever, polyserositis, or cutaneous inflammation. The FMF attacks last 1–3 days and have no apparent triggers. Recurrent deposition of the serum amyloid A (SAA) protein in the gut can cause intractable diarrhea, dysmotility, and recurrent abdominal pain. Gastrointestinal amyloidosis is a rare, but serious, complication of FMF. In this case report, we describe a rare case of chronic diarrhea and recurrent abdominal pain due to FMF-induced gastrointestinal amyloidosis.
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spelling doaj.art-45be1cb64175446a83a3dbe026cc9b632024-01-31T00:00:37ZengHindawi LimitedCase Reports in Gastrointestinal Medicine2090-65362024-01-01202410.1155/2024/6679725Gastric, Colonic, and Rectal Amyloidosis in the Setting of Familial Mediterranean Fever: A Unique Cause of Intractable DiarrheaLefika Bathobakae0Nida Ansari1Anas Mahmoud2Shayee Hasan3Ruhin Yuridullah4Sohail Qayyum5Sam Rae6Internal MedicineInternal MedicineInternal MedicineInternal MedicineGastroenterology and HepatologyPathology and Lab MedicineNephrology DivisionFamilial Mediterranean fever (FMF) is a hereditary disorder characterized by episodes of fever, polyserositis, or cutaneous inflammation. The FMF attacks last 1–3 days and have no apparent triggers. Recurrent deposition of the serum amyloid A (SAA) protein in the gut can cause intractable diarrhea, dysmotility, and recurrent abdominal pain. Gastrointestinal amyloidosis is a rare, but serious, complication of FMF. In this case report, we describe a rare case of chronic diarrhea and recurrent abdominal pain due to FMF-induced gastrointestinal amyloidosis.http://dx.doi.org/10.1155/2024/6679725
spellingShingle Lefika Bathobakae
Nida Ansari
Anas Mahmoud
Shayee Hasan
Ruhin Yuridullah
Sohail Qayyum
Sam Rae
Gastric, Colonic, and Rectal Amyloidosis in the Setting of Familial Mediterranean Fever: A Unique Cause of Intractable Diarrhea
Case Reports in Gastrointestinal Medicine
title Gastric, Colonic, and Rectal Amyloidosis in the Setting of Familial Mediterranean Fever: A Unique Cause of Intractable Diarrhea
title_full Gastric, Colonic, and Rectal Amyloidosis in the Setting of Familial Mediterranean Fever: A Unique Cause of Intractable Diarrhea
title_fullStr Gastric, Colonic, and Rectal Amyloidosis in the Setting of Familial Mediterranean Fever: A Unique Cause of Intractable Diarrhea
title_full_unstemmed Gastric, Colonic, and Rectal Amyloidosis in the Setting of Familial Mediterranean Fever: A Unique Cause of Intractable Diarrhea
title_short Gastric, Colonic, and Rectal Amyloidosis in the Setting of Familial Mediterranean Fever: A Unique Cause of Intractable Diarrhea
title_sort gastric colonic and rectal amyloidosis in the setting of familial mediterranean fever a unique cause of intractable diarrhea
url http://dx.doi.org/10.1155/2024/6679725
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