Clinical role of increased apolipoprotein B levels in coronary heart disease
Aim. To investigate clinical role of serum apolipoprotein B (apo B) levels in coronary heart disease (CHD). Material and methods. The study included 122 patients (mean age 49,7±7,1 years) with possible CHD diagnosis, who underwent clinical and instrumental examination. The diagnosis was confirmed by...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
1970-01-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1478 |
| Summary: | Aim. To investigate clinical role of serum apolipoprotein B (apo B) levels in coronary heart disease (CHD). Material and methods. The study included 122 patients (mean age 49,7±7,1 years) with possible CHD diagnosis, who underwent clinical and instrumental examination. The diagnosis was confirmed by anamnesis data, stress tests and coronary angiography results. Apo B concentration was measured by immune-enzyme method. Results. In women, sensitivity of elevated apo B levels was lower than that of hypercholesterolemia (HCH); nevertheless, specificity of both parameters was similar. In men, HCH was more sensitive and specific than increased apo B levels. Conclusion. Substantial differences in sensitivity and specificity of increased apo B levels were observed in women and men with possible CHD, as well as in various groups of men. |
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| ISSN: | 1728-8800 2619-0125 |