Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study
Abstract We examined the association between maternal air purifier use during pregnancy and neurodevelopmental delay in toddlers by analysing data from 82,457 mother-toddler pairs. Air purifier use was measured using a simple yes/no question. Developmental delays at 1.5, 2.0, 2.5, and 3.0 years were...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-09-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-98482-y |
| _version_ | 1818346195363299328 |
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| author | Kenta Matsumura Kei Hamazaki Akiko Tsuchida Hidekuni Inadera The Japan Environment and Children’s Study (JECS) Group |
| author_facet | Kenta Matsumura Kei Hamazaki Akiko Tsuchida Hidekuni Inadera The Japan Environment and Children’s Study (JECS) Group |
| author_sort | Kenta Matsumura |
| collection | DOAJ |
| description | Abstract We examined the association between maternal air purifier use during pregnancy and neurodevelopmental delay in toddlers by analysing data from 82,457 mother-toddler pairs. Air purifier use was measured using a simple yes/no question. Developmental delays at 1.5, 2.0, 2.5, and 3.0 years were assessed using the Ages and Stages Questionnaire, Third Edition. Generalized additive mixed model analysis with 21 covariates revealed that air purifier use was associated with lower prevalence of developmental delay in all five areas—communication, gross motor, fine motor, problem solving, and personal-social—at all four time points (adjusted risk ratios ranged from 0.827 to 0.927, and only one 95% confidence interval crossed the reference). These findings suggest a negative association between air purifier use during pregnancy and neurodevelopmental delay in toddlers. Trial registration: UMIN000030786 (15/01/2018). |
| first_indexed | 2024-12-13T17:14:24Z |
| format | Article |
| id | doaj.art-45c9cd1adb844ffd908425d078576e31 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-13T17:14:24Z |
| publishDate | 2021-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-45c9cd1adb844ffd908425d078576e312022-12-21T23:37:28ZengNature PortfolioScientific Reports2045-23222021-09-011111910.1038/s41598-021-98482-yProspective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s StudyKenta Matsumura0Kei Hamazaki1Akiko Tsuchida2Hidekuni Inadera3The Japan Environment and Children’s Study (JECS) GroupDepartment of Public Health, Faculty of Medicine, University of ToyamaDepartment of Public Health, Faculty of Medicine, University of ToyamaDepartment of Public Health, Faculty of Medicine, University of ToyamaDepartment of Public Health, Faculty of Medicine, University of ToyamaAbstract We examined the association between maternal air purifier use during pregnancy and neurodevelopmental delay in toddlers by analysing data from 82,457 mother-toddler pairs. Air purifier use was measured using a simple yes/no question. Developmental delays at 1.5, 2.0, 2.5, and 3.0 years were assessed using the Ages and Stages Questionnaire, Third Edition. Generalized additive mixed model analysis with 21 covariates revealed that air purifier use was associated with lower prevalence of developmental delay in all five areas—communication, gross motor, fine motor, problem solving, and personal-social—at all four time points (adjusted risk ratios ranged from 0.827 to 0.927, and only one 95% confidence interval crossed the reference). These findings suggest a negative association between air purifier use during pregnancy and neurodevelopmental delay in toddlers. Trial registration: UMIN000030786 (15/01/2018).https://doi.org/10.1038/s41598-021-98482-y |
| spellingShingle | Kenta Matsumura Kei Hamazaki Akiko Tsuchida Hidekuni Inadera The Japan Environment and Children’s Study (JECS) Group Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study Scientific Reports |
| title | Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study |
| title_full | Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study |
| title_fullStr | Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study |
| title_full_unstemmed | Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study |
| title_short | Prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the Japan Environment and Children’s Study |
| title_sort | prospective association of air purifier use during pregnancy with the neurodevelopment of toddlers in the japan environment and children s study |
| url | https://doi.org/10.1038/s41598-021-98482-y |
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