Paracentesis-induced circulatory dysfunction: are there albumin alternatives?
Abstract Background Ascites is one of the main complications of advanced liver cirrhosis. It is defined as a pathological accumulation if free fluid in the peritoneal cavity. Main body of the abstract Ascites is a sign of decompensation in patients with liver cirrhosis and is associated with decreas...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2020-08-01
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| Series: | Egyptian Liver Journal |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s43066-020-00047-7 |
| _version_ | 1818151569792696320 |
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| author | Ayman Alsebaey Eman Rewisha Imam Waked |
| author_facet | Ayman Alsebaey Eman Rewisha Imam Waked |
| author_sort | Ayman Alsebaey |
| collection | DOAJ |
| description | Abstract Background Ascites is one of the main complications of advanced liver cirrhosis. It is defined as a pathological accumulation if free fluid in the peritoneal cavity. Main body of the abstract Ascites is a sign of decompensation in patients with liver cirrhosis and is associated with decreased survival. Ascites is associated with bad cosmetic figure and poor quality of life. Ascites is a predisposing factor for developing hydrothorax, hernias, diastolic dysfunction, spontaneous bacterial peritonitis, and renal impairment especially hepatorenal syndrome. The main treatment is salt restriction and diuretics. By the time the patient become non-responder and develop tense ascites, abdominal large volume paracentesis is the treatment of choice. Its advantages are rapid, cheap, and 1 day hospitalization. The main drawback is the development of paracentesis-induced circulatory dysfunction (PICD) if no volume expanding drugs are used. PICD is associated with dilutional hyponatremia, renal impairment, so it is considered the silent killer. Albumin infusion is the standard preventive measure but since costly to other alternatives such as colloids, vasoconstrictors or lowering the standard doses of the albumin was studied and is promising. Conclusions This review summarized the effectiveness of other alternative drugs. |
| first_indexed | 2024-12-11T13:40:55Z |
| format | Article |
| id | doaj.art-45cbb9066cf046dba2bdcc8533fea707 |
| institution | Directory Open Access Journal |
| issn | 2090-6226 |
| language | English |
| last_indexed | 2024-12-11T13:40:55Z |
| publishDate | 2020-08-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Egyptian Liver Journal |
| spelling | doaj.art-45cbb9066cf046dba2bdcc8533fea7072022-12-22T01:04:45ZengSpringerOpenEgyptian Liver Journal2090-62262020-08-011011610.1186/s43066-020-00047-7Paracentesis-induced circulatory dysfunction: are there albumin alternatives?Ayman Alsebaey0Eman Rewisha1Imam Waked2Department of Hepatology and Gastroenterology, National Liver Institute, Menoufia UniversityDepartment of Hepatology and Gastroenterology, National Liver Institute, Menoufia UniversityDepartment of Hepatology and Gastroenterology, National Liver Institute, Menoufia UniversityAbstract Background Ascites is one of the main complications of advanced liver cirrhosis. It is defined as a pathological accumulation if free fluid in the peritoneal cavity. Main body of the abstract Ascites is a sign of decompensation in patients with liver cirrhosis and is associated with decreased survival. Ascites is associated with bad cosmetic figure and poor quality of life. Ascites is a predisposing factor for developing hydrothorax, hernias, diastolic dysfunction, spontaneous bacterial peritonitis, and renal impairment especially hepatorenal syndrome. The main treatment is salt restriction and diuretics. By the time the patient become non-responder and develop tense ascites, abdominal large volume paracentesis is the treatment of choice. Its advantages are rapid, cheap, and 1 day hospitalization. The main drawback is the development of paracentesis-induced circulatory dysfunction (PICD) if no volume expanding drugs are used. PICD is associated with dilutional hyponatremia, renal impairment, so it is considered the silent killer. Albumin infusion is the standard preventive measure but since costly to other alternatives such as colloids, vasoconstrictors or lowering the standard doses of the albumin was studied and is promising. Conclusions This review summarized the effectiveness of other alternative drugs.http://link.springer.com/article/10.1186/s43066-020-00047-7AscitesLarge volume paracentesisAlbuminParacentesis-induced circulatory dysfunction |
| spellingShingle | Ayman Alsebaey Eman Rewisha Imam Waked Paracentesis-induced circulatory dysfunction: are there albumin alternatives? Egyptian Liver Journal Ascites Large volume paracentesis Albumin Paracentesis-induced circulatory dysfunction |
| title | Paracentesis-induced circulatory dysfunction: are there albumin alternatives? |
| title_full | Paracentesis-induced circulatory dysfunction: are there albumin alternatives? |
| title_fullStr | Paracentesis-induced circulatory dysfunction: are there albumin alternatives? |
| title_full_unstemmed | Paracentesis-induced circulatory dysfunction: are there albumin alternatives? |
| title_short | Paracentesis-induced circulatory dysfunction: are there albumin alternatives? |
| title_sort | paracentesis induced circulatory dysfunction are there albumin alternatives |
| topic | Ascites Large volume paracentesis Albumin Paracentesis-induced circulatory dysfunction |
| url | http://link.springer.com/article/10.1186/s43066-020-00047-7 |
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