Iron deficiency promotes aortic media degeneration by activating endoplasmic reticulum stress-mediated IRE1 signaling pathway

Iron deficiency promotes aortic media degeneration by activating endoplasmic reticulum stress-mediated IRE1 signaling pathway

Background: Aortic dissection (AD) is a macrovascular disease which is pathologically characterized by aortic media degeneration (AMD). Our team's previous research found that iron deficiency (ID) promoted the formation of AMD through presentative research. In this study, we aimed to investigat...

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Bibliographic Details
Main Authors: Feng Shi, Zhiwei Wang, Qi Wu, Xiaohan Zhong, Min Zhang, Bowen Li, Wei Ren, Shun Yuan, Yuanyang Chen
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Pharmacological Research
Subjects:
Aortic dissection
Aortic media degeneration
Iron deficiency
Endoplasmic reticulum stress
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661822003115

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http://www.sciencedirect.com/science/article/pii/S1043661822003115

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