Comparative yield of transbronchial cryo-nodal biopsy, transbronchial intra-nodal forceps biopsy, and transbronchial needle aspiration for mediastinal lesions at a tertiary care center in India (COLD-FORCEPS study)
Endobronchial ultrasound (EBUS) guided mediastinal cryobiopsy, and intranodal forceps biopsy are newer modalities for sampling mediastinal lymph nodes. The data regarding the diagnostic yield of both modalities is scarce. Patients were recruited retrospectively from our existing database. Patients...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2024-01-01
|
| Series: | Monaldi Archives for Chest Disease |
| Subjects: | |
| Online Access: | https://www.monaldi-archives.org/index.php/macd/article/view/2813 |
| _version_ | 1797354552581685248 |
|---|---|
| author | Manu Madan AJ Mahendran Rohit Kumar Yash Kedia Rajnish Kaushik Pranav Ish Shibdas Chakrabarti Neeraj Kumar Gupta Nitesh Gupta |
| author_facet | Manu Madan AJ Mahendran Rohit Kumar Yash Kedia Rajnish Kaushik Pranav Ish Shibdas Chakrabarti Neeraj Kumar Gupta Nitesh Gupta |
| author_sort | Manu Madan |
| collection | DOAJ |
| description |
Endobronchial ultrasound (EBUS) guided mediastinal cryobiopsy, and intranodal forceps biopsy are newer modalities for sampling mediastinal lymph nodes. The data regarding the diagnostic yield of both modalities is scarce. Patients were recruited retrospectively from our existing database. Patients who had undergone both an EBUS guided mediastinal cryobiopsy and an intranodal forceps biopsy were enrolled in the study. The final diagnosis was made with a clinical-pathological-radiological assessment and clinico-radiological follow-up after one month. A total of 34 patients were enrolled in the study who had undergone both EBUS guided mediastinal cryobiopsy and intranodal forceps biopsy and had complete data available, including 1-month follow-up data. The sample adequacy rate of EBUS-transbronchial needle aspiration (EBUS-TBNA), EBUS-TBNA with mediastinal cryobiopsy, and EBUS-TBNA with intranodal forceps biopsy was 94.11%, 97.05%, and 94.11%, respectively (p=0.56). The diagnostic yield achieved in EBUS-TBNA, EBUS-TBNA with mediastinal cryobiopsy, and EBUS-TBNA with intranodal forceps biopsy was 73.52%, 82.35%, and 79.41%, respectively (p=0.38). No major complications were seen in any patient. To conclude, adding EBUS guided mediastinal cryobiopsy and intranodal forceps biopsy to EBUS-TBNA may not be superior to routine EBUS-TBNA.
|
| first_indexed | 2024-03-08T13:52:05Z |
| format | Article |
| id | doaj.art-45ccefe3716a499db68d2a1997009f44 |
| institution | Directory Open Access Journal |
| issn | 1122-0643 2532-5264 |
| language | English |
| last_indexed | 2024-03-08T13:52:05Z |
| publishDate | 2024-01-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Monaldi Archives for Chest Disease |
| spelling | doaj.art-45ccefe3716a499db68d2a1997009f442024-01-15T19:25:46ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642024-01-0110.4081/monaldi.2024.2813Comparative yield of transbronchial cryo-nodal biopsy, transbronchial intra-nodal forceps biopsy, and transbronchial needle aspiration for mediastinal lesions at a tertiary care center in India (COLD-FORCEPS study)Manu Madan0AJ Mahendran1Rohit Kumar2Yash Kedia3Rajnish Kaushik4Pranav Ish5Shibdas Chakrabarti6Neeraj Kumar Gupta7Nitesh Gupta8Department of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New DelhiDepartment of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New DelhiDepartment of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New DelhiDepartment of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New DelhiDepartment of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New DelhiDepartment of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New DelhiDepartment of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New DelhiDepartment of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New DelhiDepartment of Pulmonary, Critical Care and Sleep Medicine, VMMC and Safdarjung Hospital, New Delhi Endobronchial ultrasound (EBUS) guided mediastinal cryobiopsy, and intranodal forceps biopsy are newer modalities for sampling mediastinal lymph nodes. The data regarding the diagnostic yield of both modalities is scarce. Patients were recruited retrospectively from our existing database. Patients who had undergone both an EBUS guided mediastinal cryobiopsy and an intranodal forceps biopsy were enrolled in the study. The final diagnosis was made with a clinical-pathological-radiological assessment and clinico-radiological follow-up after one month. A total of 34 patients were enrolled in the study who had undergone both EBUS guided mediastinal cryobiopsy and intranodal forceps biopsy and had complete data available, including 1-month follow-up data. The sample adequacy rate of EBUS-transbronchial needle aspiration (EBUS-TBNA), EBUS-TBNA with mediastinal cryobiopsy, and EBUS-TBNA with intranodal forceps biopsy was 94.11%, 97.05%, and 94.11%, respectively (p=0.56). The diagnostic yield achieved in EBUS-TBNA, EBUS-TBNA with mediastinal cryobiopsy, and EBUS-TBNA with intranodal forceps biopsy was 73.52%, 82.35%, and 79.41%, respectively (p=0.38). No major complications were seen in any patient. To conclude, adding EBUS guided mediastinal cryobiopsy and intranodal forceps biopsy to EBUS-TBNA may not be superior to routine EBUS-TBNA. https://www.monaldi-archives.org/index.php/macd/article/view/2813Lymph nodesmediastinumendoscopic ultrasound-guided fine needle aspiration/methodsultrasonographyinterventional |
| spellingShingle | Manu Madan AJ Mahendran Rohit Kumar Yash Kedia Rajnish Kaushik Pranav Ish Shibdas Chakrabarti Neeraj Kumar Gupta Nitesh Gupta Comparative yield of transbronchial cryo-nodal biopsy, transbronchial intra-nodal forceps biopsy, and transbronchial needle aspiration for mediastinal lesions at a tertiary care center in India (COLD-FORCEPS study) Monaldi Archives for Chest Disease Lymph nodes mediastinum endoscopic ultrasound-guided fine needle aspiration/methods ultrasonography interventional |
| title | Comparative yield of transbronchial cryo-nodal biopsy, transbronchial intra-nodal forceps biopsy, and transbronchial needle aspiration for mediastinal lesions at a tertiary care center in India (COLD-FORCEPS study) |
| title_full | Comparative yield of transbronchial cryo-nodal biopsy, transbronchial intra-nodal forceps biopsy, and transbronchial needle aspiration for mediastinal lesions at a tertiary care center in India (COLD-FORCEPS study) |
| title_fullStr | Comparative yield of transbronchial cryo-nodal biopsy, transbronchial intra-nodal forceps biopsy, and transbronchial needle aspiration for mediastinal lesions at a tertiary care center in India (COLD-FORCEPS study) |
| title_full_unstemmed | Comparative yield of transbronchial cryo-nodal biopsy, transbronchial intra-nodal forceps biopsy, and transbronchial needle aspiration for mediastinal lesions at a tertiary care center in India (COLD-FORCEPS study) |
| title_short | Comparative yield of transbronchial cryo-nodal biopsy, transbronchial intra-nodal forceps biopsy, and transbronchial needle aspiration for mediastinal lesions at a tertiary care center in India (COLD-FORCEPS study) |
| title_sort | comparative yield of transbronchial cryo nodal biopsy transbronchial intra nodal forceps biopsy and transbronchial needle aspiration for mediastinal lesions at a tertiary care center in india cold forceps study |
| topic | Lymph nodes mediastinum endoscopic ultrasound-guided fine needle aspiration/methods ultrasonography interventional |
| url | https://www.monaldi-archives.org/index.php/macd/article/view/2813 |
| work_keys_str_mv | AT manumadan comparativeyieldoftransbronchialcryonodalbiopsytransbronchialintranodalforcepsbiopsyandtransbronchialneedleaspirationformediastinallesionsatatertiarycarecenterinindiacoldforcepsstudy AT ajmahendran comparativeyieldoftransbronchialcryonodalbiopsytransbronchialintranodalforcepsbiopsyandtransbronchialneedleaspirationformediastinallesionsatatertiarycarecenterinindiacoldforcepsstudy AT rohitkumar comparativeyieldoftransbronchialcryonodalbiopsytransbronchialintranodalforcepsbiopsyandtransbronchialneedleaspirationformediastinallesionsatatertiarycarecenterinindiacoldforcepsstudy AT yashkedia comparativeyieldoftransbronchialcryonodalbiopsytransbronchialintranodalforcepsbiopsyandtransbronchialneedleaspirationformediastinallesionsatatertiarycarecenterinindiacoldforcepsstudy AT rajnishkaushik comparativeyieldoftransbronchialcryonodalbiopsytransbronchialintranodalforcepsbiopsyandtransbronchialneedleaspirationformediastinallesionsatatertiarycarecenterinindiacoldforcepsstudy AT pranavish comparativeyieldoftransbronchialcryonodalbiopsytransbronchialintranodalforcepsbiopsyandtransbronchialneedleaspirationformediastinallesionsatatertiarycarecenterinindiacoldforcepsstudy AT shibdaschakrabarti comparativeyieldoftransbronchialcryonodalbiopsytransbronchialintranodalforcepsbiopsyandtransbronchialneedleaspirationformediastinallesionsatatertiarycarecenterinindiacoldforcepsstudy AT neerajkumargupta comparativeyieldoftransbronchialcryonodalbiopsytransbronchialintranodalforcepsbiopsyandtransbronchialneedleaspirationformediastinallesionsatatertiarycarecenterinindiacoldforcepsstudy AT niteshgupta comparativeyieldoftransbronchialcryonodalbiopsytransbronchialintranodalforcepsbiopsyandtransbronchialneedleaspirationformediastinallesionsatatertiarycarecenterinindiacoldforcepsstudy |