Diacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell Polarity

Diacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell Polarity

Diacylglycerol kinases (DGKs) terminate diacylglycerol (DAG) signaling and promote phosphatidic acid (PA) production. Isoform specific regulation of DGKs activity and localization allows DGKs to shape the DAG and PA gradients. The capacity of DGKs to constrain the areas of DAG signaling is exemplifi...

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Bibliographic Details
Main Authors:	Gianluca Baldanzi, Valentina Bettio, Valeria Malacarne, Andrea Graziani
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-11-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	Cell Polarity localization Migration Lipid domain Immune Synpse
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00140/full

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