Perbandingan Sekuens Konsensus Gen Hemaglutinin Virus Avian Influenza Subtipe H5N1 Asal Unggas di Indonesia dengan Subtipe H5N2 dan H5N9

Consensus sequence of hemagglutinin (HA) gene of avian influenza viruses of H5N1 subtype isolatedfrom fowl in Indonesia – hereafter named as H5N1_Indonesia – is compared with that of H5N2 and H5N9viruses. Sequence information were downloaded from the public database GeneBank. The genetic distancesan...

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Main Authors: I Gusti Ngurah Kade Mahardika, I Nyoman Suartha, Ida Bagus Kade Suardana, I Gusti Ayu Yuniati Kencana, I Wayan Teguh Wibawan
Format: Article
Language:English
Published: Universitas Udayana 2009-03-01
Series:Jurnal Veteriner
Online Access:http://ojs.unud.ac.id/index.php/jvet/article/view/3341
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author I Gusti Ngurah Kade Mahardika
I Nyoman Suartha
Ida Bagus Kade Suardana
I Gusti Ayu Yuniati Kencana
I Wayan Teguh Wibawan
author_facet I Gusti Ngurah Kade Mahardika
I Nyoman Suartha
Ida Bagus Kade Suardana
I Gusti Ayu Yuniati Kencana
I Wayan Teguh Wibawan
author_sort I Gusti Ngurah Kade Mahardika
collection DOAJ
description Consensus sequence of hemagglutinin (HA) gene of avian influenza viruses of H5N1 subtype isolatedfrom fowl in Indonesia – hereafter named as H5N1_Indonesia – is compared with that of H5N2 and H5N9viruses. Sequence information were downloaded from the public database GeneBank. The genetic distancesand nucleotide as well as its deduced amino-acid sequence alignment were analysed. At nucleotide level,genetic distances of HA between H5N1_Indonesia to H5N2 and H5N9 are 16.2% and 9.6%, respectively.At amino-acid level, the distances are 9.7% and 6.8%. The genetic distances of HA1 fragments are 19.0%(H5N1_Indonesia – H5N2) and 10.9% (H5N1_Indonesia – H5N9). At amino-acid, level the genetic distancesof HA1 are 13.1% (H5N1_Indonesia-H5N2) and 8.8% (H5N1_Indonesia – H5N9). All three subtypes havedifferent glycosilation motive and variation of amino-acid sequence of four antigenic sites. The consequenceof those facts is discussed.
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spelling doaj.art-45d1603ba835442db043ef2150179f782022-12-21T18:21:33ZengUniversitas UdayanaJurnal Veteriner1411-83272477-56652009-03-011013174Perbandingan Sekuens Konsensus Gen Hemaglutinin Virus Avian Influenza Subtipe H5N1 Asal Unggas di Indonesia dengan Subtipe H5N2 dan H5N9I Gusti Ngurah Kade MahardikaI Nyoman SuarthaIda Bagus Kade SuardanaI Gusti Ayu Yuniati KencanaI Wayan Teguh WibawanConsensus sequence of hemagglutinin (HA) gene of avian influenza viruses of H5N1 subtype isolatedfrom fowl in Indonesia – hereafter named as H5N1_Indonesia – is compared with that of H5N2 and H5N9viruses. Sequence information were downloaded from the public database GeneBank. The genetic distancesand nucleotide as well as its deduced amino-acid sequence alignment were analysed. At nucleotide level,genetic distances of HA between H5N1_Indonesia to H5N2 and H5N9 are 16.2% and 9.6%, respectively.At amino-acid level, the distances are 9.7% and 6.8%. The genetic distances of HA1 fragments are 19.0%(H5N1_Indonesia – H5N2) and 10.9% (H5N1_Indonesia – H5N9). At amino-acid, level the genetic distancesof HA1 are 13.1% (H5N1_Indonesia-H5N2) and 8.8% (H5N1_Indonesia – H5N9). All three subtypes havedifferent glycosilation motive and variation of amino-acid sequence of four antigenic sites. The consequenceof those facts is discussed.http://ojs.unud.ac.id/index.php/jvet/article/view/3341
spellingShingle I Gusti Ngurah Kade Mahardika
I Nyoman Suartha
Ida Bagus Kade Suardana
I Gusti Ayu Yuniati Kencana
I Wayan Teguh Wibawan
Perbandingan Sekuens Konsensus Gen Hemaglutinin Virus Avian Influenza Subtipe H5N1 Asal Unggas di Indonesia dengan Subtipe H5N2 dan H5N9
Jurnal Veteriner
title Perbandingan Sekuens Konsensus Gen Hemaglutinin Virus Avian Influenza Subtipe H5N1 Asal Unggas di Indonesia dengan Subtipe H5N2 dan H5N9
title_full Perbandingan Sekuens Konsensus Gen Hemaglutinin Virus Avian Influenza Subtipe H5N1 Asal Unggas di Indonesia dengan Subtipe H5N2 dan H5N9
title_fullStr Perbandingan Sekuens Konsensus Gen Hemaglutinin Virus Avian Influenza Subtipe H5N1 Asal Unggas di Indonesia dengan Subtipe H5N2 dan H5N9
title_full_unstemmed Perbandingan Sekuens Konsensus Gen Hemaglutinin Virus Avian Influenza Subtipe H5N1 Asal Unggas di Indonesia dengan Subtipe H5N2 dan H5N9
title_short Perbandingan Sekuens Konsensus Gen Hemaglutinin Virus Avian Influenza Subtipe H5N1 Asal Unggas di Indonesia dengan Subtipe H5N2 dan H5N9
title_sort perbandingan sekuens konsensus gen hemaglutinin virus avian influenza subtipe h5n1 asal unggas di indonesia dengan subtipe h5n2 dan h5n9
url http://ojs.unud.ac.id/index.php/jvet/article/view/3341
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