Adult-Onset greither's disease: A rare report of two cases
Inherited palmoplantar keratodermas (PPKs) have onset in the late infancy or early childhood and have a positive family history. Sporadic cases and cases with onset in adulthood have been rarely reported. We describe two female cases with transgradiens and progradiens PPK, with onset in adulthood ha...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2023-01-01
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Series: | Journal of Dermatology and Dermatologic Surgery |
Subjects: | |
Online Access: | http://www.jddsjournal.org/article.asp?issn=2352-2410;year=2023;volume=27;issue=1;spage=39;epage=41;aulast=Khan |
Summary: | Inherited palmoplantar keratodermas (PPKs) have onset in the late infancy or early childhood and have a positive family history. Sporadic cases and cases with onset in adulthood have been rarely reported. We describe two female cases with transgradiens and progradiens PPK, with onset in adulthood having clinical and histological features of Greither's disease (GD). Only a single report of adult-onset GD has been reported in the literature. All patients presenting with palmoplantar keratoderma should be thoroughly evaluated, as it may be a late-onset inherited disorder, it adds to the spectrum of conditions to presenting with PPKs of late-onset. |
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ISSN: | 2352-2410 2352-2429 |