Adult-Onset greither's disease: A rare report of two cases

Inherited palmoplantar keratodermas (PPKs) have onset in the late infancy or early childhood and have a positive family history. Sporadic cases and cases with onset in adulthood have been rarely reported. We describe two female cases with transgradiens and progradiens PPK, with onset in adulthood ha...

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Bibliographic Details
Main Authors: Hania Q Khan, Ayesha Sharmeen, Syed S Amin, Bushra Siddiqui
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Dermatology and Dermatologic Surgery
Subjects:
Online Access:http://www.jddsjournal.org/article.asp?issn=2352-2410;year=2023;volume=27;issue=1;spage=39;epage=41;aulast=Khan
Description
Summary:Inherited palmoplantar keratodermas (PPKs) have onset in the late infancy or early childhood and have a positive family history. Sporadic cases and cases with onset in adulthood have been rarely reported. We describe two female cases with transgradiens and progradiens PPK, with onset in adulthood having clinical and histological features of Greither's disease (GD). Only a single report of adult-onset GD has been reported in the literature. All patients presenting with palmoplantar keratoderma should be thoroughly evaluated, as it may be a late-onset inherited disorder, it adds to the spectrum of conditions to presenting with PPKs of late-onset.
ISSN:2352-2410
2352-2429