The effect of povidone-iodine 2% eye drops in the treatment of adenoviral keratoconjunctivitis
BACKGROUND: Keratoconjunctivitis is one of the most common pathologies worldwide, caused by several infectious and noninfectious factors. This study aimed to determine the effect of povidone-iodine 2% eye drops in treating adenoviral keratoconjunctivitis. METHODS: This analytic cross-sectional study...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Oman Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ojoonline.org/article.asp?issn=0974-620X;year=2023;volume=16;issue=1;spage=69;epage=74;aulast=Soleimani |
| _version_ | 1827986011157692416 |
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| author | Mohammad Soleimani Seyed Ali Tabatabaei Arash Mirzaei Amirreza Esfandiari Mahdi Soleymanzadeh Reza Sadeghi Afagh Hassanzadeh Rad |
| author_facet | Mohammad Soleimani Seyed Ali Tabatabaei Arash Mirzaei Amirreza Esfandiari Mahdi Soleymanzadeh Reza Sadeghi Afagh Hassanzadeh Rad |
| author_sort | Mohammad Soleimani |
| collection | DOAJ |
| description | BACKGROUND: Keratoconjunctivitis is one of the most common pathologies worldwide, caused by several infectious and noninfectious factors. This study aimed to determine the effect of povidone-iodine 2% eye drops in treating adenoviral keratoconjunctivitis.
METHODS: This analytic cross-sectional study was conducted on patients referred to Farabi Eye Hospital Records of patients with adenoviral keratoconjunctivitis, more than 12 years of age, and no allergy to iodine who were treated by povidone-iodine 2% eye drops four times a day were assessed. Data included demographic characteristics, family history of adenoviral keratoconjunctivitis, follicular conjunctivitis, petechial conjunctival hemorrhages, periauricular lymphadenopathy, and the presence of conjunctival pseudomembrane were collected from the records. Discharge decrease, injection decrease, swelling decrease, pseudomembrane formation, periauricular lymphadenopathy, and subepithelial infiltration on the 7th day of assessment by physical examination were reported.
RESULTS: Patients with a mean (±standard deviation) age of 33.77 (11.01) years were assessed. At the baseline, 95 (99.0%) follicular conjunctivitis, 94 (97.9%) petechial conjunctival hemorrhages, 29 (30.2%) periauricular lymphadenopathy, and 5 (5.2%) conjunctival pseudomembrane were recorded. On the 7th day of treatment, the discharge decreased in 92.7% of patients, and the injection decreased in 90.6%. The swelling decrease was also detected in 79.2% of patients. Subepithelial infiltration was only seen in 21.9% of the study population. Results showed that 2.1% of patients had periauricular lymphadenopathy, and only 13 out of 96 patients (13.5%) had pseudomembrane formation after 7 days.
CONCLUSIONS: Based on the safety, availability, and tolerability of povidone-iodine and its promising effects on patients with adenoviral keratoconjunctivitis, further clinical trials assessing the impact of this drug in a longer duration of follow-up can be recommended. |
| first_indexed | 2024-04-09T23:23:58Z |
| format | Article |
| id | doaj.art-45dca09148034939affa1555fafedd2a |
| institution | Directory Open Access Journal |
| issn | 0974-620X |
| language | English |
| last_indexed | 2024-04-09T23:23:58Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Oman Journal of Ophthalmology |
| spelling | doaj.art-45dca09148034939affa1555fafedd2a2023-03-21T11:25:38ZengWolters Kluwer Medknow PublicationsOman Journal of Ophthalmology0974-620X2023-01-01161697410.4103/ojo.ojo_180_22The effect of povidone-iodine 2% eye drops in the treatment of adenoviral keratoconjunctivitisMohammad SoleimaniSeyed Ali TabatabaeiArash MirzaeiAmirreza EsfandiariMahdi SoleymanzadehReza SadeghiAfagh Hassanzadeh RadBACKGROUND: Keratoconjunctivitis is one of the most common pathologies worldwide, caused by several infectious and noninfectious factors. This study aimed to determine the effect of povidone-iodine 2% eye drops in treating adenoviral keratoconjunctivitis. METHODS: This analytic cross-sectional study was conducted on patients referred to Farabi Eye Hospital Records of patients with adenoviral keratoconjunctivitis, more than 12 years of age, and no allergy to iodine who were treated by povidone-iodine 2% eye drops four times a day were assessed. Data included demographic characteristics, family history of adenoviral keratoconjunctivitis, follicular conjunctivitis, petechial conjunctival hemorrhages, periauricular lymphadenopathy, and the presence of conjunctival pseudomembrane were collected from the records. Discharge decrease, injection decrease, swelling decrease, pseudomembrane formation, periauricular lymphadenopathy, and subepithelial infiltration on the 7th day of assessment by physical examination were reported. RESULTS: Patients with a mean (±standard deviation) age of 33.77 (11.01) years were assessed. At the baseline, 95 (99.0%) follicular conjunctivitis, 94 (97.9%) petechial conjunctival hemorrhages, 29 (30.2%) periauricular lymphadenopathy, and 5 (5.2%) conjunctival pseudomembrane were recorded. On the 7th day of treatment, the discharge decreased in 92.7% of patients, and the injection decreased in 90.6%. The swelling decrease was also detected in 79.2% of patients. Subepithelial infiltration was only seen in 21.9% of the study population. Results showed that 2.1% of patients had periauricular lymphadenopathy, and only 13 out of 96 patients (13.5%) had pseudomembrane formation after 7 days. CONCLUSIONS: Based on the safety, availability, and tolerability of povidone-iodine and its promising effects on patients with adenoviral keratoconjunctivitis, further clinical trials assessing the impact of this drug in a longer duration of follow-up can be recommended.http://www.ojoonline.org/article.asp?issn=0974-620X;year=2023;volume=16;issue=1;spage=69;epage=74;aulast=Soleimanikeratoconjunctivitislymphadenopathypovidone-iodine |
| spellingShingle | Mohammad Soleimani Seyed Ali Tabatabaei Arash Mirzaei Amirreza Esfandiari Mahdi Soleymanzadeh Reza Sadeghi Afagh Hassanzadeh Rad The effect of povidone-iodine 2% eye drops in the treatment of adenoviral keratoconjunctivitis Oman Journal of Ophthalmology keratoconjunctivitis lymphadenopathy povidone-iodine |
| title | The effect of povidone-iodine 2% eye drops in the treatment of adenoviral keratoconjunctivitis |
| title_full | The effect of povidone-iodine 2% eye drops in the treatment of adenoviral keratoconjunctivitis |
| title_fullStr | The effect of povidone-iodine 2% eye drops in the treatment of adenoviral keratoconjunctivitis |
| title_full_unstemmed | The effect of povidone-iodine 2% eye drops in the treatment of adenoviral keratoconjunctivitis |
| title_short | The effect of povidone-iodine 2% eye drops in the treatment of adenoviral keratoconjunctivitis |
| title_sort | effect of povidone iodine 2 eye drops in the treatment of adenoviral keratoconjunctivitis |
| topic | keratoconjunctivitis lymphadenopathy povidone-iodine |
| url | http://www.ojoonline.org/article.asp?issn=0974-620X;year=2023;volume=16;issue=1;spage=69;epage=74;aulast=Soleimani |
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