Protection of multiple ischemic organs by controlled reperfusion

Reperfusion injury (RI) is a harmful complication that takes place during recanalization treatment of ischemic organs. Currently, there are no efficacious treatments for protecting the organs against RI. Therefore, it is necessary to discover new strategies to prevent RI. As a novel intervention tec...

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Main Authors: Jin Ma, Ming Li, Mengke Zhang, Miuwen Jiang, Yuan Gao, Ruchi Mangal, Yuchuan Ding, Zhichen Yin, Xunming Ji
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Brain Circulation
Subjects:
Online Access:http://www.braincirculation.org/article.asp?issn=2394-8108;year=2021;volume=7;issue=4;spage=241;epage=246;aulast=Ma
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author Jin Ma
Ming Li
Mengke Zhang
Miuwen Jiang
Yuan Gao
Ruchi Mangal
Yuchuan Ding
Zhichen Yin
Xunming Ji
author_facet Jin Ma
Ming Li
Mengke Zhang
Miuwen Jiang
Yuan Gao
Ruchi Mangal
Yuchuan Ding
Zhichen Yin
Xunming Ji
author_sort Jin Ma
collection DOAJ
description Reperfusion injury (RI) is a harmful complication that takes place during recanalization treatment of ischemic organs. Currently, there are no efficacious treatments for protecting the organs against RI. Therefore, it is necessary to discover new strategies to prevent RI. As a novel intervention technique, controlled reperfusion has promising effects on protecting multiple organs from RI, and it is done by adjusting physical parameters of blood flow or chemical compositions of the reperfusion liquid. In this brief review, the status of various controlled reperfusion methods is presented, as well as their application in the protection of ischemic organs.
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spelling doaj.art-45dedb277ce84db2803db4090451b8022022-12-22T04:03:43ZengWolters Kluwer Medknow PublicationsBrain Circulation2455-46262021-01-017424124610.4103/bc.bc_59_21Protection of multiple ischemic organs by controlled reperfusionJin MaMing LiMengke ZhangMiuwen JiangYuan GaoRuchi MangalYuchuan DingZhichen YinXunming JiReperfusion injury (RI) is a harmful complication that takes place during recanalization treatment of ischemic organs. Currently, there are no efficacious treatments for protecting the organs against RI. Therefore, it is necessary to discover new strategies to prevent RI. As a novel intervention technique, controlled reperfusion has promising effects on protecting multiple organs from RI, and it is done by adjusting physical parameters of blood flow or chemical compositions of the reperfusion liquid. In this brief review, the status of various controlled reperfusion methods is presented, as well as their application in the protection of ischemic organs.http://www.braincirculation.org/article.asp?issn=2394-8108;year=2021;volume=7;issue=4;spage=241;epage=246;aulast=Macontrolled reperfusionorgan protectionreperfusion injury
spellingShingle Jin Ma
Ming Li
Mengke Zhang
Miuwen Jiang
Yuan Gao
Ruchi Mangal
Yuchuan Ding
Zhichen Yin
Xunming Ji
Protection of multiple ischemic organs by controlled reperfusion
Brain Circulation
controlled reperfusion
organ protection
reperfusion injury
title Protection of multiple ischemic organs by controlled reperfusion
title_full Protection of multiple ischemic organs by controlled reperfusion
title_fullStr Protection of multiple ischemic organs by controlled reperfusion
title_full_unstemmed Protection of multiple ischemic organs by controlled reperfusion
title_short Protection of multiple ischemic organs by controlled reperfusion
title_sort protection of multiple ischemic organs by controlled reperfusion
topic controlled reperfusion
organ protection
reperfusion injury
url http://www.braincirculation.org/article.asp?issn=2394-8108;year=2021;volume=7;issue=4;spage=241;epage=246;aulast=Ma
work_keys_str_mv AT jinma protectionofmultipleischemicorgansbycontrolledreperfusion
AT mingli protectionofmultipleischemicorgansbycontrolledreperfusion
AT mengkezhang protectionofmultipleischemicorgansbycontrolledreperfusion
AT miuwenjiang protectionofmultipleischemicorgansbycontrolledreperfusion
AT yuangao protectionofmultipleischemicorgansbycontrolledreperfusion
AT ruchimangal protectionofmultipleischemicorgansbycontrolledreperfusion
AT yuchuanding protectionofmultipleischemicorgansbycontrolledreperfusion
AT zhichenyin protectionofmultipleischemicorgansbycontrolledreperfusion
AT xunmingji protectionofmultipleischemicorgansbycontrolledreperfusion