Efficacy of clofazimine and nitazoxanide combination in treating intestinal cryptosporidiosis and enhancing intestinal cellular regeneration in immunocompromised mice

Efficacy of clofazimine and nitazoxanide combination in treating intestinal cryptosporidiosis and enhancing intestinal cellular regeneration in immunocompromised mice

Cryptosporidium is a widely distributed food and water-borne enteric protozoan that affects a wide range of vertebrates, resulting in life-threatening consequences, particularly in immunocompromised hosts. The lack of effective anti-cryptosporidial drugs may be related to the parasite's unique...

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Bibliographic Details
Main Authors: Marwa Esmat, Amany A. Abdel-Aal, Maisa A. Shalaby, Manal Badawi, Hala Elaskary, Ahmed Badawi Yousif, Mennat-Elrahman A. Fahmy
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Food and Waterborne Parasitology
Subjects:
Cryptosporidium
Clofazimine
Ultrastructure
TEM
Intestinal renewal
Online Access:http://www.sciencedirect.com/science/article/pii/S240567662200018X

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