Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients
Excellent water-absorbing nanofiber meshes were developed as a potential material for removing excess fluids from the blood of chronic renal failure patients toward a wearable blood purification system without requiring specialized equipment. The nanofiber meshes were successfully fabricated from po...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-05-01
|
| Series: | Fibers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6439/7/5/39 |
| _version_ | 1811184237220462592 |
|---|---|
| author | Mirei Tsuge Kanoko Takahashi Rio Kurimoto Ailifeire Fulati Koichiro Uto Akihiko Kikuchi Mitsuhiro Ebara |
| author_facet | Mirei Tsuge Kanoko Takahashi Rio Kurimoto Ailifeire Fulati Koichiro Uto Akihiko Kikuchi Mitsuhiro Ebara |
| author_sort | Mirei Tsuge |
| collection | DOAJ |
| description | Excellent water-absorbing nanofiber meshes were developed as a potential material for removing excess fluids from the blood of chronic renal failure patients toward a wearable blood purification system without requiring specialized equipment. The nanofiber meshes were successfully fabricated from poly(acrylic acid) (PAA) under various applied voltages by appropriately setting the electrospinning conditions. The electrospun PAA nanofibers were thermally crosslinked via heat treatment and then neutralized from their carboxylic acid form (PAA) to a sodium carboxylate form poly(sodium acrylate) (PSA). The PSA nanofiber meshes exhibited a specific surface area 393 times that of the PSA film. The PSA fiber meshes showed a much faster and higher swelling than its corresponding film, owing to the higher capillary forces from the fibers in addition to the water absorption of the PSA gel itself. The proposed PSA fibers have the potential to be utilized in a new approach to remove excess water from the bloodstream without requiring specialized equipment. |
| first_indexed | 2024-04-11T13:08:59Z |
| format | Article |
| id | doaj.art-45e15055f85a479bb4d42ffe8f0b0a21 |
| institution | Directory Open Access Journal |
| issn | 2079-6439 |
| language | English |
| last_indexed | 2024-04-11T13:08:59Z |
| publishDate | 2019-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Fibers |
| spelling | doaj.art-45e15055f85a479bb4d42ffe8f0b0a212022-12-22T04:22:38ZengMDPI AGFibers2079-64392019-05-01753910.3390/fib7050039fib7050039Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure PatientsMirei Tsuge0Kanoko Takahashi1Rio Kurimoto2Ailifeire Fulati3Koichiro Uto4Akihiko Kikuchi5Mitsuhiro Ebara6Graduate School of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, JapanGraduate School of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, JapanInternational Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), Tsukuba, Ibaraki 305-0044, JapanGraduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8577, JapanInternational Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), Tsukuba, Ibaraki 305-0044, JapanGraduate School of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, JapanGraduate School of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, JapanExcellent water-absorbing nanofiber meshes were developed as a potential material for removing excess fluids from the blood of chronic renal failure patients toward a wearable blood purification system without requiring specialized equipment. The nanofiber meshes were successfully fabricated from poly(acrylic acid) (PAA) under various applied voltages by appropriately setting the electrospinning conditions. The electrospun PAA nanofibers were thermally crosslinked via heat treatment and then neutralized from their carboxylic acid form (PAA) to a sodium carboxylate form poly(sodium acrylate) (PSA). The PSA nanofiber meshes exhibited a specific surface area 393 times that of the PSA film. The PSA fiber meshes showed a much faster and higher swelling than its corresponding film, owing to the higher capillary forces from the fibers in addition to the water absorption of the PSA gel itself. The proposed PSA fibers have the potential to be utilized in a new approach to remove excess water from the bloodstream without requiring specialized equipment.https://www.mdpi.com/2079-6439/7/5/39water absorbing materialsnanofiberselectrospinningpoly(sodium acrylate)hemodialysis |
| spellingShingle | Mirei Tsuge Kanoko Takahashi Rio Kurimoto Ailifeire Fulati Koichiro Uto Akihiko Kikuchi Mitsuhiro Ebara Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients Fibers water absorbing materials nanofibers electrospinning poly(sodium acrylate) hemodialysis |
| title | Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients |
| title_full | Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients |
| title_fullStr | Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients |
| title_full_unstemmed | Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients |
| title_short | Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients |
| title_sort | fabrication of water absorbing nanofiber meshes toward an efficient removal of excess water from kidney failure patients |
| topic | water absorbing materials nanofibers electrospinning poly(sodium acrylate) hemodialysis |
| url | https://www.mdpi.com/2079-6439/7/5/39 |
| work_keys_str_mv | AT mireitsuge fabricationofwaterabsorbingnanofibermeshestowardanefficientremovalofexcesswaterfromkidneyfailurepatients AT kanokotakahashi fabricationofwaterabsorbingnanofibermeshestowardanefficientremovalofexcesswaterfromkidneyfailurepatients AT riokurimoto fabricationofwaterabsorbingnanofibermeshestowardanefficientremovalofexcesswaterfromkidneyfailurepatients AT ailifeirefulati fabricationofwaterabsorbingnanofibermeshestowardanefficientremovalofexcesswaterfromkidneyfailurepatients AT koichirouto fabricationofwaterabsorbingnanofibermeshestowardanefficientremovalofexcesswaterfromkidneyfailurepatients AT akihikokikuchi fabricationofwaterabsorbingnanofibermeshestowardanefficientremovalofexcesswaterfromkidneyfailurepatients AT mitsuhiroebara fabricationofwaterabsorbingnanofibermeshestowardanefficientremovalofexcesswaterfromkidneyfailurepatients |