A Proof-of-Concept Study on the Therapeutic Potential of Au Nanoparticles Radiolabeled with the Alpha-Emitter Actinium-225

A Proof-of-Concept Study on the Therapeutic Potential of Au Nanoparticles Radiolabeled with the Alpha-Emitter Actinium-225

Actinium-225 (<sup>225</sup>Ac) is receiving increased attention for its application in targeted radionuclide therapy, due to the short range of its emitted alpha particles in conjunction with their high linear energy transfer, which lead to the eradication of tumor cells while sparing n...

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Bibliographic Details
Main Authors: Evangelia-Alexandra Salvanou, Dimitris Stellas, Charalampos Tsoukalas, Barbara Mavroidi, Maria Paravatou-Petsotas, Nikolaos Kalogeropoulos, Stavros Xanthopoulos, Franck Denat, Gautier Laurent, Rana Bazzi, Stephane Roux, Penelope Bouziotis
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
actinium-225
alpha emitters
gold nanoparticles
radiolabeling
brachytherapy
cancer therapy
Online Access:https://www.mdpi.com/1999-4923/12/2/188

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https://www.mdpi.com/1999-4923/12/2/188

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