Identification of a Complex Karyotype Signature with Clinical Implications in AML and MDS-EB Using Gene Expression Profiling

Identification of a Complex Karyotype Signature with Clinical Implications in AML and MDS-EB Using Gene Expression Profiling

Complex karyotype (CK) is associated with a poor prognosis in both acute myeloid leukemia (AML) and myelodysplastic syndrome with excess blasts (MDS-EB). Transcriptomic analyses have improved our understanding of the disease and risk stratification of myeloid neoplasms; however, CK-specific gene exp...

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Bibliographic Details
Main Authors: Cheonghwa Lee, Ha Nui Kim, Jung Ah Kwon, Jinha Hwang, Ji-Ye Park, Ok Sarah Shin, Soo-Young Yoon, Jung Yoon
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cancers
Subjects:
complex karyotype
AML
MDS
gene expression
SOD1
Online Access:https://www.mdpi.com/2072-6694/15/21/5289

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