Association Between Pulsatile Components of Blood Pressure and Severe Tooth Loss in Rural Ecuador: The Three Villages Study
Background: Arterial hypertension has been associated with severe tooth loss, but differential associations with individual components of blood pressure (BP) have scarcely been investigated. We assessed the independent associations between pulsatile/steady components of BP and severe tooth loss in c...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2020-05-01
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| Series: | Journal of Primary Care & Community Health |
| Online Access: | https://doi.org/10.1177/2150132720928670 |
| _version_ | 1830461706334109696 |
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| author | Oscar H. Del Brutto Robertino M. Mera Bettsy Y. Recalde Andrew P. Torpey John P. Hill Laura M. Generale Leslie D. Peralta Mark J. Sedler MPH |
| author_facet | Oscar H. Del Brutto Robertino M. Mera Bettsy Y. Recalde Andrew P. Torpey John P. Hill Laura M. Generale Leslie D. Peralta Mark J. Sedler MPH |
| author_sort | Oscar H. Del Brutto |
| collection | DOAJ |
| description | Background: Arterial hypertension has been associated with severe tooth loss, but differential associations with individual components of blood pressure (BP) have scarcely been investigated. We assessed the independent associations between pulsatile/steady components of BP and severe tooth loss in community-dwelling adults residing in 3 rural Ecuadorian villages. Methods: Individuals aged ≥40 years living in Atahualpa, El Tambo, and Prosperidad were identified during door-to-door surveys. Data collection focused on the number of remaining teeth and measurements of pulsatile/steady components of BP. Multivariate models were fitted to assess independent associations between pulsatile/steady BP components and severe tooth loss, after adjusting for relevant covariates. Results: A total of 1543 individuals were included. Oral exams identified 426 (28%) individuals with severe tooth loss. BP levels ≥140/90 mm Hg were determined in 481 (31%) individuals. The mean pulse pressure (PP) level was 55.3 ± 19 mm Hg. For systolic BP (SBP), the mean level was 133.1 ± 23.5 mm Hg, and for diastolic BP (DBP) it was 77.8 ± 11.5 mm Hg. Univariate models showed significant associations between severe tooth loss and SBP and PP, but not with DBP. However, the significance was taken away in fully adjusted generalized linear models. Age remained as an independent significant covariate in models using SBP and PP. Causal mediation analyses disclosed that percentages of the effect of severe tooth loss mediated by age were 99.5% for SBP and 98.9% for PP. Conclusion: This study shows that age captures most of the effect of the association between pulsatile components of BP and severe tooth loss. |
| first_indexed | 2024-12-21T11:33:55Z |
| format | Article |
| id | doaj.art-45ed15f67b8649799c49ee0aaf2e63e3 |
| institution | Directory Open Access Journal |
| issn | 2150-1327 |
| language | English |
| last_indexed | 2024-12-21T11:33:55Z |
| publishDate | 2020-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Primary Care & Community Health |
| spelling | doaj.art-45ed15f67b8649799c49ee0aaf2e63e32022-12-21T19:05:29ZengSAGE PublishingJournal of Primary Care & Community Health2150-13272020-05-011110.1177/2150132720928670Association Between Pulsatile Components of Blood Pressure and Severe Tooth Loss in Rural Ecuador: The Three Villages StudyOscar H. Del Brutto0Robertino M. Mera1Bettsy Y. Recalde2Andrew P. Torpey3John P. Hill4Laura M. Generale5Leslie D. Peralta6Mark J. Sedler MPH7Universidad Espíritu Santo–Ecuador, Samborondón, EcuadorGilead Sciences, Inc, Foster City, CA, USAUniversidad Espíritu Santo–Ecuador, Samborondón, EcuadorStony Brook University, New York, NY, USAStony Brook University, New York, NY, USAStony Brook University, New York, NY, USAStony Brook University, New York, NY, USAStony Brook University, New York, NY, USABackground: Arterial hypertension has been associated with severe tooth loss, but differential associations with individual components of blood pressure (BP) have scarcely been investigated. We assessed the independent associations between pulsatile/steady components of BP and severe tooth loss in community-dwelling adults residing in 3 rural Ecuadorian villages. Methods: Individuals aged ≥40 years living in Atahualpa, El Tambo, and Prosperidad were identified during door-to-door surveys. Data collection focused on the number of remaining teeth and measurements of pulsatile/steady components of BP. Multivariate models were fitted to assess independent associations between pulsatile/steady BP components and severe tooth loss, after adjusting for relevant covariates. Results: A total of 1543 individuals were included. Oral exams identified 426 (28%) individuals with severe tooth loss. BP levels ≥140/90 mm Hg were determined in 481 (31%) individuals. The mean pulse pressure (PP) level was 55.3 ± 19 mm Hg. For systolic BP (SBP), the mean level was 133.1 ± 23.5 mm Hg, and for diastolic BP (DBP) it was 77.8 ± 11.5 mm Hg. Univariate models showed significant associations between severe tooth loss and SBP and PP, but not with DBP. However, the significance was taken away in fully adjusted generalized linear models. Age remained as an independent significant covariate in models using SBP and PP. Causal mediation analyses disclosed that percentages of the effect of severe tooth loss mediated by age were 99.5% for SBP and 98.9% for PP. Conclusion: This study shows that age captures most of the effect of the association between pulsatile components of BP and severe tooth loss.https://doi.org/10.1177/2150132720928670 |
| spellingShingle | Oscar H. Del Brutto Robertino M. Mera Bettsy Y. Recalde Andrew P. Torpey John P. Hill Laura M. Generale Leslie D. Peralta Mark J. Sedler MPH Association Between Pulsatile Components of Blood Pressure and Severe Tooth Loss in Rural Ecuador: The Three Villages Study Journal of Primary Care & Community Health |
| title | Association Between Pulsatile Components of Blood Pressure and Severe Tooth Loss in Rural Ecuador: The Three Villages Study |
| title_full | Association Between Pulsatile Components of Blood Pressure and Severe Tooth Loss in Rural Ecuador: The Three Villages Study |
| title_fullStr | Association Between Pulsatile Components of Blood Pressure and Severe Tooth Loss in Rural Ecuador: The Three Villages Study |
| title_full_unstemmed | Association Between Pulsatile Components of Blood Pressure and Severe Tooth Loss in Rural Ecuador: The Three Villages Study |
| title_short | Association Between Pulsatile Components of Blood Pressure and Severe Tooth Loss in Rural Ecuador: The Three Villages Study |
| title_sort | association between pulsatile components of blood pressure and severe tooth loss in rural ecuador the three villages study |
| url | https://doi.org/10.1177/2150132720928670 |
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