Memantine Protects against Paclitaxel-Induced Cognitive Impairment through Modulation of Neurogenesis and Inflammation in Mice

Memantine Protects against Paclitaxel-Induced Cognitive Impairment through Modulation of Neurogenesis and Inflammation in Mice

Chemotherapy-induced cognitive impairment (CICI) is an adverse side effect of cancer treatment with increasing awareness. Hippocampal damage and related neurocognitive impairment may mediate the development of CICI, in which altered neurogenesis may play a role. In addition, increased inflammation m...

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Bibliographic Details
Main Authors:	Pi-Shan Sung, Pei-Wen Chen, Chia-Jui Yen, Meng-Ru Shen, Chih-Hung Chen, Kuen-Jer Tsai, Chou-Ching K. Lin
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Series:	Cancers
Subjects:	chemotherapy-induced cognitive impairment paclitaxel neurogenesis brain-derived neurotrophic factor inflammation neuroinflammation
Online Access:	https://www.mdpi.com/2072-6694/13/16/4177

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