Discovery of New Hydrazone-Thiazole Polyphenolic Antioxidants through Computer-Aided Design and In Vitro Experimental Validation

Discovery of New Hydrazone-Thiazole Polyphenolic Antioxidants through Computer-Aided Design and In Vitro Experimental Validation

Oxidative stress is linked to a series of diseases; therefore, the development of efficient antioxidants might be beneficial in preventing or ameliorating these conditions. Based on the structure of a previously reported compound with good antioxidant properties and on computational studies, we desi...

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Bibliographic Details
Main Authors: Gabriel Marc, Anca Stana, Mihaela Tertiş, Cecilia Cristea, Alexandra Ciorîţă, Ștefan-Mihai Drăgan, Vlad-Alexandru Toma, Raluca Borlan, Monica Focșan, Adrian Pîrnău, Laurian Vlase, Smaranda Oniga, Ovidiu Oniga
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
catechol
hydrazone
thiazole
computer-aided design
synthesis
antioxidant
Online Access:https://www.mdpi.com/1422-0067/24/17/13277

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