Nut sensitization profile in Southern Taiwan
Background/purpose: To evaluate the relationship between serum-specific immunoglobulin E (IgE) to peanuts/tree nuts and their clinical manifestations in atopic diseases. Method: Serum from people with the classical symptoms of asthma, allergic rhinitis (AR), or atopic dermatitis (AD) was collected f...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-10-01
|
| Series: | Journal of Microbiology, Immunology and Infection |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S168411821830149X |
| _version_ | 1818155915638996992 |
|---|---|
| author | Chih-Wei Cheng Yung-Chih Lin Bao-Ren Nong Po-Yen Liu Yung-Feng Huang Ling-Ying Lu Herng-Sheng Lee |
| author_facet | Chih-Wei Cheng Yung-Chih Lin Bao-Ren Nong Po-Yen Liu Yung-Feng Huang Ling-Ying Lu Herng-Sheng Lee |
| author_sort | Chih-Wei Cheng |
| collection | DOAJ |
| description | Background/purpose: To evaluate the relationship between serum-specific immunoglobulin E (IgE) to peanuts/tree nuts and their clinical manifestations in atopic diseases. Method: Serum from people with the classical symptoms of asthma, allergic rhinitis (AR), or atopic dermatitis (AD) was collected for the measurement of serum-specific IgE to peanuts, cashew nuts, Brazil nuts, almonds, and coconuts. Cases with possible sensitization to these nuts (serum specific IgE ≧ 0.35 kU/L) were selected and their clinical relationships with physician-diagnosed asthma, allergic rhinitis, or atopic dermatitis were analyzed. Result: Compared with non-sensitization group, people with peanut/tree nut sensitization have higher prevalence of atopic dermatitis, but no such difference noted in the prevalence of allergic rhinitis. In the situation of asthma, people with sensitization to peanuts and Brazil nuts, but not other nuts, have higher prevalence of asthma than people without sensitization to any nut (p < 0.001 and p < 0.05, respectively). Binary logistic regression analysis also showed positive associations between peanut (OR: 1.164, p value = 0.017) and Brazil nut (OR: 1.304, p value = 0.055) sensitization and asthma. The associations between peanut and Brazil nut sensitization and asthma were independent of the prevalence of other atopic diseases. Conclusion: People in Asia may have less severe allergic effects as in Western countries, but sensitization to specific food allergens such as peanuts or Brazil nuts may predispose individuals to asthma, which could be helpful in diagnosis and deserves more attention than previously considered. |
| first_indexed | 2024-12-11T14:49:59Z |
| format | Article |
| id | doaj.art-45f424faf87d4bcda56008884658988c |
| institution | Directory Open Access Journal |
| issn | 1684-1182 |
| language | English |
| last_indexed | 2024-12-11T14:49:59Z |
| publishDate | 2020-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Microbiology, Immunology and Infection |
| spelling | doaj.art-45f424faf87d4bcda56008884658988c2022-12-22T01:01:30ZengElsevierJournal of Microbiology, Immunology and Infection1684-11822020-10-01535791796Nut sensitization profile in Southern TaiwanChih-Wei Cheng0Yung-Chih Lin1Bao-Ren Nong2Po-Yen Liu3Yung-Feng Huang4Ling-Ying Lu5Herng-Sheng Lee6Department of Pediatrics, Kaohsiung Veterans General Hospital, Number 386, Dazhong 1st Road, Zuoying District, Kaohsiung City 813, TaiwanDepartment of Pediatrics, Taipei Veterans General Hospital, Taitung Branch, Taitung, TaiwanDepartment of Pediatrics, Kaohsiung Veterans General Hospital, Number 386, Dazhong 1st Road, Zuoying District, Kaohsiung City 813, Taiwan; Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDepartment of Pediatrics, Kaohsiung Veterans General Hospital, Number 386, Dazhong 1st Road, Zuoying District, Kaohsiung City 813, TaiwanDepartment of Pediatrics, Kaohsiung Veterans General Hospital, Number 386, Dazhong 1st Road, Zuoying District, Kaohsiung City 813, Taiwan; Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; Wellem Medical Group, Hangzhou, China; Corresponding author. No.8 Lane 121 Bansin Road Banciao District, New Taipei City 22052, Taiwan. Fax: +886 7 3468207.Division of Allergy, Immunology and Rheumatology, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, TaiwanDepartment of Pathology and Laboratory, Kaohsiung Veterans General Hospital, Kaohsiung, TaiwanBackground/purpose: To evaluate the relationship between serum-specific immunoglobulin E (IgE) to peanuts/tree nuts and their clinical manifestations in atopic diseases. Method: Serum from people with the classical symptoms of asthma, allergic rhinitis (AR), or atopic dermatitis (AD) was collected for the measurement of serum-specific IgE to peanuts, cashew nuts, Brazil nuts, almonds, and coconuts. Cases with possible sensitization to these nuts (serum specific IgE ≧ 0.35 kU/L) were selected and their clinical relationships with physician-diagnosed asthma, allergic rhinitis, or atopic dermatitis were analyzed. Result: Compared with non-sensitization group, people with peanut/tree nut sensitization have higher prevalence of atopic dermatitis, but no such difference noted in the prevalence of allergic rhinitis. In the situation of asthma, people with sensitization to peanuts and Brazil nuts, but not other nuts, have higher prevalence of asthma than people without sensitization to any nut (p < 0.001 and p < 0.05, respectively). Binary logistic regression analysis also showed positive associations between peanut (OR: 1.164, p value = 0.017) and Brazil nut (OR: 1.304, p value = 0.055) sensitization and asthma. The associations between peanut and Brazil nut sensitization and asthma were independent of the prevalence of other atopic diseases. Conclusion: People in Asia may have less severe allergic effects as in Western countries, but sensitization to specific food allergens such as peanuts or Brazil nuts may predispose individuals to asthma, which could be helpful in diagnosis and deserves more attention than previously considered.http://www.sciencedirect.com/science/article/pii/S168411821830149XPeanut sensitizationBrazil nut sensitizationSpecific IgEAsthmaAtopic diseases |
| spellingShingle | Chih-Wei Cheng Yung-Chih Lin Bao-Ren Nong Po-Yen Liu Yung-Feng Huang Ling-Ying Lu Herng-Sheng Lee Nut sensitization profile in Southern Taiwan Journal of Microbiology, Immunology and Infection Peanut sensitization Brazil nut sensitization Specific IgE Asthma Atopic diseases |
| title | Nut sensitization profile in Southern Taiwan |
| title_full | Nut sensitization profile in Southern Taiwan |
| title_fullStr | Nut sensitization profile in Southern Taiwan |
| title_full_unstemmed | Nut sensitization profile in Southern Taiwan |
| title_short | Nut sensitization profile in Southern Taiwan |
| title_sort | nut sensitization profile in southern taiwan |
| topic | Peanut sensitization Brazil nut sensitization Specific IgE Asthma Atopic diseases |
| url | http://www.sciencedirect.com/science/article/pii/S168411821830149X |
| work_keys_str_mv | AT chihweicheng nutsensitizationprofileinsoutherntaiwan AT yungchihlin nutsensitizationprofileinsoutherntaiwan AT baorennong nutsensitizationprofileinsoutherntaiwan AT poyenliu nutsensitizationprofileinsoutherntaiwan AT yungfenghuang nutsensitizationprofileinsoutherntaiwan AT lingyinglu nutsensitizationprofileinsoutherntaiwan AT herngshenglee nutsensitizationprofileinsoutherntaiwan |