Effect of Trimethine Cyanine Dye- and Folate-Conjugation on the In Vitro Biological Activity of Proapoptotic Peptides

Effect of Trimethine Cyanine Dye- and Folate-Conjugation on the In Vitro Biological Activity of Proapoptotic Peptides

Despite continuous advances, anticancer therapy still faces several technical hurdles, such as selectivity on cellular and subcellular targets of therapeutics. Toward addressing these limitations, we have combined the use of proapoptotic peptides, trimethine cyanine dye, and folate to target the mit...

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Bibliographic Details
Main Authors: Davide Cardella, Wenjing Deng, Louis Y. P. Luk, Yu-Hsuan Tsai
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
cancer
cyanine dyes
folate
mitochondria
proapoptotic peptides
solid-phase synthesis
Online Access:https://www.mdpi.com/2218-273X/12/5/725

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