Ambient particulate matter pollution on lipid peroxidation in cardiovascular diseases

Cardiovascular diseases refer to all disorders related to the heart and its circulatory system, such as atherosclerosis, arrhythmia, hypertension, and stroke. In recent years, numerous environmental studies in humans and animal models have confirmed a positive association between ambient particulate...

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Main Authors: Lea Ulintz, Qinghua Sun
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Environmental Disease
Subjects:
Online Access:http://www.environmentmed.org/article.asp?issn=2468-5690;year=2016;volume=1;issue=4;spage=109;epage=117;aulast=Ulintz
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author Lea Ulintz
Qinghua Sun
author_facet Lea Ulintz
Qinghua Sun
author_sort Lea Ulintz
collection DOAJ
description Cardiovascular diseases refer to all disorders related to the heart and its circulatory system, such as atherosclerosis, arrhythmia, hypertension, and stroke. In recent years, numerous environmental studies in humans and animal models have confirmed a positive association between ambient particulate matter (PM) exposure and cardiovascular morbidity/mortality. The deleterious impacts of the exposure are involved in multiple mechanisms, in which one is due to the pro-inflammatory effects that result from the peroxidation of lipids, which provide critical structure and function in cellular membranes, the main sites of pollutant attack. This review aims to assess the current scientific literature relating to pertinent mechanisms, molecular pathways, and at-risk populations associated with cardiovascular complications induced by ambient PM exposure.
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spelling doaj.art-45f88932e6a749dd839f6e2897751a182022-12-22T01:44:53ZengWolters Kluwer Medknow PublicationsEnvironmental Disease2468-56902468-57042016-01-011410911710.4103/2468-5690.198616Ambient particulate matter pollution on lipid peroxidation in cardiovascular diseasesLea UlintzQinghua SunCardiovascular diseases refer to all disorders related to the heart and its circulatory system, such as atherosclerosis, arrhythmia, hypertension, and stroke. In recent years, numerous environmental studies in humans and animal models have confirmed a positive association between ambient particulate matter (PM) exposure and cardiovascular morbidity/mortality. The deleterious impacts of the exposure are involved in multiple mechanisms, in which one is due to the pro-inflammatory effects that result from the peroxidation of lipids, which provide critical structure and function in cellular membranes, the main sites of pollutant attack. This review aims to assess the current scientific literature relating to pertinent mechanisms, molecular pathways, and at-risk populations associated with cardiovascular complications induced by ambient PM exposure.http://www.environmentmed.org/article.asp?issn=2468-5690;year=2016;volume=1;issue=4;spage=109;epage=117;aulast=UlintzAmbient particulate matter pollutioncardiovascular diseaseslipid peroxidation
spellingShingle Lea Ulintz
Qinghua Sun
Ambient particulate matter pollution on lipid peroxidation in cardiovascular diseases
Environmental Disease
Ambient particulate matter pollution
cardiovascular diseases
lipid peroxidation
title Ambient particulate matter pollution on lipid peroxidation in cardiovascular diseases
title_full Ambient particulate matter pollution on lipid peroxidation in cardiovascular diseases
title_fullStr Ambient particulate matter pollution on lipid peroxidation in cardiovascular diseases
title_full_unstemmed Ambient particulate matter pollution on lipid peroxidation in cardiovascular diseases
title_short Ambient particulate matter pollution on lipid peroxidation in cardiovascular diseases
title_sort ambient particulate matter pollution on lipid peroxidation in cardiovascular diseases
topic Ambient particulate matter pollution
cardiovascular diseases
lipid peroxidation
url http://www.environmentmed.org/article.asp?issn=2468-5690;year=2016;volume=1;issue=4;spage=109;epage=117;aulast=Ulintz
work_keys_str_mv AT leaulintz ambientparticulatematterpollutiononlipidperoxidationincardiovasculardiseases
AT qinghuasun ambientparticulatematterpollutiononlipidperoxidationincardiovasculardiseases