IMVAMUNE<sup>®</sup> and ACAM2000<sup>®</sup> Provide Different Protection against Disease When Administered Postexposure in an Intranasal Monkeypox Challenge Prairie Dog Model

IMVAMUNE<sup>®</sup> and ACAM2000<sup>®</sup> Provide Different Protection against Disease When Administered Postexposure in an Intranasal Monkeypox Challenge Prairie Dog Model

The protection provided by smallpox vaccines when used after exposure to Orthopoxviruses is poorly understood. Postexposu re administration of 1st generation smallpox vaccines was effective during eradication. However, historical epidemiological reports and animal studies on postexposure vaccination...

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Bibliographic Details
Main Authors: M. Shannon Keckler, Johanna S Salzer, Nishi Patel, Michael B Townsend, Yoshinori J Nakazawa, Jeffrey B Doty, Nadia F Gallardo-Romero, Panayampalli S Satheshkumar, Darin S Carroll, Kevin L Karem, Inger K Damon
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Vaccines
Subjects:
monkeypox virus
postexposure vaccination
smallpox vaccines
prairie dog model
Online Access:https://www.mdpi.com/2076-393X/8/3/396

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