Fabrication of Curcumin@Ag Loaded Core/Shell Nanofiber Membrane and its Synergistic Antibacterial Properties
The core/shell structure nanofiber membrane loaded with curcumin and silver nanoparticles was prepared by coaxial electrospinning technology, which is a high-efficiency combined antibacterial material composed of photodynamic antibacterial agent and metal nanoparticle. As a photosensitizer, curcumin...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-03-01
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| Series: | Frontiers in Chemistry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2022.870666/full |
| _version_ | 1828855987540328448 |
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| author | Qiuxiang Wang Songlin Liu Wenjuan Lu Pingping Zhang |
| author_facet | Qiuxiang Wang Songlin Liu Wenjuan Lu Pingping Zhang |
| author_sort | Qiuxiang Wang |
| collection | DOAJ |
| description | The core/shell structure nanofiber membrane loaded with curcumin and silver nanoparticles was prepared by coaxial electrospinning technology, which is a high-efficiency combined antibacterial material composed of photodynamic antibacterial agent and metal nanoparticle. As a photosensitizer, curcumin could generate singlet oxygen under laser irradiation. Silver nanoparticles have antibacterial properties, and could also enhance the singlet oxygen production of curcumin due to the metal-enhanced singlet oxygen effect, thereby producing a synergistic antibacterial effect. Compared with the antibacterial rate of uniaxial curcumin fiber membrane (45.65%) and uniaxial silver nanoparticle-loaded fiber membrane (66.96%), the antibacterial rate of curcumin@Ag core/shell structure fiber membrane against Staphylococcus aureus is as high as 93.04%. In addition, the antibacterial experiments show that the core/shell fiber membrane also has excellent antibacterial effects on Escherichia coli. |
| first_indexed | 2024-12-13T01:05:06Z |
| format | Article |
| id | doaj.art-4602988b47664bfabb58a5acb9ecf612 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-12-13T01:05:06Z |
| publishDate | 2022-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-4602988b47664bfabb58a5acb9ecf6122022-12-22T00:04:34ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462022-03-011010.3389/fchem.2022.870666870666Fabrication of Curcumin@Ag Loaded Core/Shell Nanofiber Membrane and its Synergistic Antibacterial PropertiesQiuxiang WangSonglin LiuWenjuan LuPingping ZhangThe core/shell structure nanofiber membrane loaded with curcumin and silver nanoparticles was prepared by coaxial electrospinning technology, which is a high-efficiency combined antibacterial material composed of photodynamic antibacterial agent and metal nanoparticle. As a photosensitizer, curcumin could generate singlet oxygen under laser irradiation. Silver nanoparticles have antibacterial properties, and could also enhance the singlet oxygen production of curcumin due to the metal-enhanced singlet oxygen effect, thereby producing a synergistic antibacterial effect. Compared with the antibacterial rate of uniaxial curcumin fiber membrane (45.65%) and uniaxial silver nanoparticle-loaded fiber membrane (66.96%), the antibacterial rate of curcumin@Ag core/shell structure fiber membrane against Staphylococcus aureus is as high as 93.04%. In addition, the antibacterial experiments show that the core/shell fiber membrane also has excellent antibacterial effects on Escherichia coli.https://www.frontiersin.org/articles/10.3389/fchem.2022.870666/fullphotodynamic antibacterialcurcuminsilver nanoparticleselectrospinningcore/shell fiberssynergistic antibacterial properties |
| spellingShingle | Qiuxiang Wang Songlin Liu Wenjuan Lu Pingping Zhang Fabrication of Curcumin@Ag Loaded Core/Shell Nanofiber Membrane and its Synergistic Antibacterial Properties Frontiers in Chemistry photodynamic antibacterial curcumin silver nanoparticles electrospinning core/shell fibers synergistic antibacterial properties |
| title | Fabrication of Curcumin@Ag Loaded Core/Shell Nanofiber Membrane and its Synergistic Antibacterial Properties |
| title_full | Fabrication of Curcumin@Ag Loaded Core/Shell Nanofiber Membrane and its Synergistic Antibacterial Properties |
| title_fullStr | Fabrication of Curcumin@Ag Loaded Core/Shell Nanofiber Membrane and its Synergistic Antibacterial Properties |
| title_full_unstemmed | Fabrication of Curcumin@Ag Loaded Core/Shell Nanofiber Membrane and its Synergistic Antibacterial Properties |
| title_short | Fabrication of Curcumin@Ag Loaded Core/Shell Nanofiber Membrane and its Synergistic Antibacterial Properties |
| title_sort | fabrication of curcumin ag loaded core shell nanofiber membrane and its synergistic antibacterial properties |
| topic | photodynamic antibacterial curcumin silver nanoparticles electrospinning core/shell fibers synergistic antibacterial properties |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2022.870666/full |
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