Diagnosis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-2)
One of the most problematic issues in hematological malignancies is the diagnosis of invasive fungal diseases. Especially, the difficulty of mycological diagnosis and the necessity of immediate intervention in molds have led to the adoption of 'surrogate markers' which does not verify, but...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2014-12-01
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| Series: | Turkish Journal of Hematology |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-91297 |
| _version_ | 1797916765653565440 |
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| author | Sevtap Arıkan Akdağlı Alpay Azap Figen Başaran Demirkazık Beyza Ener Sibel Aşcıoğlu Hayran Özlem Özdemir Kumbasar Gökhan Metan Zekaver Odabaşı Ömrüm Uzun Hamdi Akan |
| author_facet | Sevtap Arıkan Akdağlı Alpay Azap Figen Başaran Demirkazık Beyza Ener Sibel Aşcıoğlu Hayran Özlem Özdemir Kumbasar Gökhan Metan Zekaver Odabaşı Ömrüm Uzun Hamdi Akan |
| author_sort | Sevtap Arıkan Akdağlı |
| collection | DOAJ |
| description | One of the most problematic issues in hematological malignancies is the diagnosis of invasive fungal diseases. Especially, the difficulty of mycological diagnosis and the necessity of immediate intervention in molds have led to the adoption of 'surrogate markers' which does not verify, but strongly suggests fungal infection. The markers commonly used are galactomannan (GM), beta-glucan and imaging methods. Although there are numerous studies on these diagnostic approaches, none of these markers serve as a support for the clinician, as is in human immunodeficiency virus (HIV) or cytomegalovirus (CMV) infections. This paper has been prepared to explain the diagnostic tests and show the clinician how the available resources can be used. As moleculer tests have not been standardized and not used routinely in the clinics, they will not be mentioned here. |
| first_indexed | 2024-04-10T13:02:30Z |
| format | Article |
| id | doaj.art-46035a34d4ab4e6980994f8bf5007d62 |
| institution | Directory Open Access Journal |
| issn | 1308-5263 |
| language | English |
| last_indexed | 2024-04-10T13:02:30Z |
| publishDate | 2014-12-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Turkish Journal of Hematology |
| spelling | doaj.art-46035a34d4ab4e6980994f8bf5007d622023-02-15T16:13:06ZengGalenos Publishing HouseTurkish Journal of Hematology1308-52632014-12-0131434235610.4274/tjh.2014.0218TJH-91297Diagnosis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-2)Sevtap Arıkan Akdağlı0Alpay Azap1Figen Başaran Demirkazık2Beyza Ener3Sibel Aşcıoğlu Hayran4Özlem Özdemir Kumbasar5Gökhan Metan6Zekaver Odabaşı7Ömrüm Uzun8Hamdi Akan9Hacettepe University, Faculty Of Medicine, Department Of Medical Microbiology, Ankara, TurkeyAnkara University, Faculty Of Medicine, Department Of Infectious Diseases And Clinical Microbiology, Ankara, TurkeyHacettepe University, Faculty Of Medicine, Department Of Radiology, Ankara, TurkeyUludağ University Faculty Of Medicine, Department Of Microbiology, Bursa, TurkeyHacettepe University, Faculty Of Medicine, Department Of Infectious Diseases, Ankara, TurkeyAnkara University, Faculty Of Medicine, Department Of Pulmonary Diseases, Ankara, TurkeyErciyes University, Faculty Of Medicine, Department Of Infectious Diseases And Clinical Microbiology, Kayseri, TurkeyMarmara University, Faculty Of Medicine, Department Of Infectious Diseases, Istanbul, TurkeyHacettepe University, Faculty Of Medicine, Department Of Infectious Diseases, Ankara, TurkeyAnkara University Medical School, Department Of Hematology, Ankara, TurkeyOne of the most problematic issues in hematological malignancies is the diagnosis of invasive fungal diseases. Especially, the difficulty of mycological diagnosis and the necessity of immediate intervention in molds have led to the adoption of 'surrogate markers' which does not verify, but strongly suggests fungal infection. The markers commonly used are galactomannan (GM), beta-glucan and imaging methods. Although there are numerous studies on these diagnostic approaches, none of these markers serve as a support for the clinician, as is in human immunodeficiency virus (HIV) or cytomegalovirus (CMV) infections. This paper has been prepared to explain the diagnostic tests and show the clinician how the available resources can be used. As moleculer tests have not been standardized and not used routinely in the clinics, they will not be mentioned here.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-91297diagnosisinvasive fungal infectionimagingserology |
| spellingShingle | Sevtap Arıkan Akdağlı Alpay Azap Figen Başaran Demirkazık Beyza Ener Sibel Aşcıoğlu Hayran Özlem Özdemir Kumbasar Gökhan Metan Zekaver Odabaşı Ömrüm Uzun Hamdi Akan Diagnosis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-2) Turkish Journal of Hematology diagnosis invasive fungal infection imaging serology |
| title | Diagnosis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-2) |
| title_full | Diagnosis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-2) |
| title_fullStr | Diagnosis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-2) |
| title_full_unstemmed | Diagnosis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-2) |
| title_short | Diagnosis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-2) |
| title_sort | diagnosis of invasive fungal diseases in hematological malignancies a critical review of evidence and turkish expert opinion teo 2 |
| topic | diagnosis invasive fungal infection imaging serology |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-91297 |
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