Super-multifactorial survey YHAB revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screening
Study Objectives: Aging is a risk factor for sleep apnoea syndrome (SAS), which is associated with lower quality of life and sudden mortality. However, SAS is often overlooked in older adults without suspicions. Therefore, this study aimed to evaluate SAS incidence and 48 other general factors in ol...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-10-01
|
| Series: | Frontiers in Aging |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fragi.2022.965199/full |
| _version_ | 1811181998444642304 |
|---|---|
| author | Yuji Tanaka Yuji Tanaka Takashi Ando Kazuki Mochizuki Satoshi Igarashi Kyoichiro Tsuchiya Kozo Saito Kozo Saito Yasumi Ito Zentaro Yamagata Masaru Iwasaki Masaru Iwasaki YHAB Health Data Survey Group 2020 |
| author_facet | Yuji Tanaka Yuji Tanaka Takashi Ando Kazuki Mochizuki Satoshi Igarashi Kyoichiro Tsuchiya Kozo Saito Kozo Saito Yasumi Ito Zentaro Yamagata Masaru Iwasaki Masaru Iwasaki YHAB Health Data Survey Group 2020 |
| author_sort | Yuji Tanaka |
| collection | DOAJ |
| description | Study Objectives: Aging is a risk factor for sleep apnoea syndrome (SAS), which is associated with lower quality of life and sudden mortality. However, SAS is often overlooked in older adults without suspicions. Therefore, this study aimed to evaluate SAS incidence and 48 other general factors in older adults.Methods: This cross-sectional study included all non-caregiver-certified, healthy individuals (N = 32) who survived during the long-term cohort study and agreed to participate in apnoea-hypopnoea index (AHI) measurement (aged 83–95 years). AHI and 48 other general factors were evaluated, and simple linear regression analysis was used to identify potential AHI-related factors. Stepwise evaluation was further performed using multiple linear regression analyses.Results: Although no individuals were previously diagnosed with SAS, 30 (93.75%) participants had some degree of SAS (AHI > 5/h), and 22 (68.75%) had severe or moderate SAS (AHI > 15/h). Compared with typical single risk factors represented by body mass index, combining daily steps and other factors improved the fit to the multiple linear regression. Combining daily steps and body mass index improved the fit for males and combining daily steps and red blood cell count improved the fit for females.Conclusion: SAS was highly prevalent in unaware healthy Japanese older adults; combinations of daily steps and body mass index, and daily steps and red blood cell count may predict AHI in such individuals without the need for a specific AHI test. |
| first_indexed | 2024-04-11T09:24:31Z |
| format | Article |
| id | doaj.art-460530c0b5964796a244766c75b1256b |
| institution | Directory Open Access Journal |
| issn | 2673-6217 |
| language | English |
| last_indexed | 2024-04-11T09:24:31Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging |
| spelling | doaj.art-460530c0b5964796a244766c75b1256b2022-12-22T04:32:03ZengFrontiers Media S.A.Frontiers in Aging2673-62172022-10-01310.3389/fragi.2022.965199965199Super-multifactorial survey YHAB revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screeningYuji Tanaka0Yuji Tanaka1Takashi Ando2Kazuki Mochizuki3Satoshi Igarashi4Kyoichiro Tsuchiya5Kozo Saito6Kozo Saito7Yasumi Ito8Zentaro Yamagata9Masaru Iwasaki10Masaru Iwasaki11 YHAB Health Data Survey Group 2020Department of Advanced Biomedical Research, Faculty of Medicine, University of Yamanashi, Yamanashi, JapanYamanashi GLIA Centre, University of Yamanashi, Yamanashi, JapanDepartment of Orthopaedic Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, JapanLaboratory of Food and Nutritional Sciences, Department of Local Produce and Food Sciences, Faculty of Life and Environmental Sciences, University of Yamanashi, Yamanashi, JapanDepartment of Otorhinolaryngology, Faculty of Medicine, University of Yamanashi, Yamanashi, JapanDepartment of Diabetes and Endocrinology, Faculty of Medicine, University of Yamanashi, Yamanashi, JapanYamanashi GLIA Centre, University of Yamanashi, Yamanashi, JapanDepartment of Neuropharmacology, Faculty of Medicine, University of Yamanashi, Yamanashi, JapanFaculty of Engineering, University of Yamanashi, Yamanashi, JapanDepartment of Health Sciences, Faculty of Medicine, University of Yamanashi, Yamanashi, JapanDepartment of Advanced Biomedical Research, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan0Department of Clinical Research Collaboration Promotion, Faculty of Medicine, University of Yamanashi, Yamanashi, JapanStudy Objectives: Aging is a risk factor for sleep apnoea syndrome (SAS), which is associated with lower quality of life and sudden mortality. However, SAS is often overlooked in older adults without suspicions. Therefore, this study aimed to evaluate SAS incidence and 48 other general factors in older adults.Methods: This cross-sectional study included all non-caregiver-certified, healthy individuals (N = 32) who survived during the long-term cohort study and agreed to participate in apnoea-hypopnoea index (AHI) measurement (aged 83–95 years). AHI and 48 other general factors were evaluated, and simple linear regression analysis was used to identify potential AHI-related factors. Stepwise evaluation was further performed using multiple linear regression analyses.Results: Although no individuals were previously diagnosed with SAS, 30 (93.75%) participants had some degree of SAS (AHI > 5/h), and 22 (68.75%) had severe or moderate SAS (AHI > 15/h). Compared with typical single risk factors represented by body mass index, combining daily steps and other factors improved the fit to the multiple linear regression. Combining daily steps and body mass index improved the fit for males and combining daily steps and red blood cell count improved the fit for females.Conclusion: SAS was highly prevalent in unaware healthy Japanese older adults; combinations of daily steps and body mass index, and daily steps and red blood cell count may predict AHI in such individuals without the need for a specific AHI test.https://www.frontiersin.org/articles/10.3389/fragi.2022.965199/fullsleepdaily stepsapnoea-hypopnoea indexolder adultshealthy longevityrespiratory frail |
| spellingShingle | Yuji Tanaka Yuji Tanaka Takashi Ando Kazuki Mochizuki Satoshi Igarashi Kyoichiro Tsuchiya Kozo Saito Kozo Saito Yasumi Ito Zentaro Yamagata Masaru Iwasaki Masaru Iwasaki YHAB Health Data Survey Group 2020 Super-multifactorial survey YHAB revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screening Frontiers in Aging sleep daily steps apnoea-hypopnoea index older adults healthy longevity respiratory frail |
| title | Super-multifactorial survey YHAB revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screening |
| title_full | Super-multifactorial survey YHAB revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screening |
| title_fullStr | Super-multifactorial survey YHAB revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screening |
| title_full_unstemmed | Super-multifactorial survey YHAB revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screening |
| title_short | Super-multifactorial survey YHAB revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screening |
| title_sort | super multifactorial survey yhab revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screening |
| topic | sleep daily steps apnoea-hypopnoea index older adults healthy longevity respiratory frail |
| url | https://www.frontiersin.org/articles/10.3389/fragi.2022.965199/full |
| work_keys_str_mv | AT yujitanaka supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT yujitanaka supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT takashiando supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT kazukimochizuki supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT satoshiigarashi supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT kyoichirotsuchiya supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT kozosaito supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT kozosaito supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT yasumiito supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT zentaroyamagata supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT masaruiwasaki supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT masaruiwasaki supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening AT yhabhealthdatasurveygroup2020 supermultifactorialsurveyyhabrevealedhighprevalenceofsleepapnoeasyndromeinunawareolderadultsandpotentialcombinatorialfactorsforitsinitialscreening |