Evaluation of changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training in women with polycystic ovary syndrome
Background: Polycystic ovary syndrome (PCOS) is a polygenic endocrine disorder in women of reproductive ages which will lead to infertility. This study is aimed to determine changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval tr...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | International Journal of Preventive Medicine |
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| Online Access: | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2019;volume=10;issue=1;spage=187;epage=187;aulast=Samadi |
| _version_ | 1818857874889113600 |
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| author | Zeinab Samadi Effat Bambaeichi Mahboubeh Valiani Zahra Shahshahan |
| author_facet | Zeinab Samadi Effat Bambaeichi Mahboubeh Valiani Zahra Shahshahan |
| author_sort | Zeinab Samadi |
| collection | DOAJ |
| description | Background: Polycystic ovary syndrome (PCOS) is a polygenic endocrine disorder in women of reproductive ages which will lead to infertility. This study is aimed to determine changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training (AHIIT) in women with PCOS. Methods: Thirty patients with PCOS having age between 20 and 35 and body mass index (BMI) ≥30 kg/m2 in obstetrics and gynaecology clinics in Isfahan were selected based on Rotterdam Diagnostic Criteria. They were randomly divided into experimental (AHIIT + metformin, N = 15) and control groups (metformin, N = 15). The exercises were done for 12 weeks, three sessions of 20 minutes. Metformin (1500 mg) was taken daily for 3 consecutive days for 12 weeks. Kolmogorov–Smirnov test, t-test, Covariance and Wilcoxon were applied (P value < 0.05). Results: After 12 weeks, no significant difference was observed in waist-to-hip ratio (WHR), but in AHIIT, the BMI and fat mass significantly decreased and levels of follicle-stimulating hormone (FSH), free testosterone (FT) and sex hormone binding globulin (SHBG) increased compared to control group (P < 0.05). While levels of improvement of total testosterone (TT), dehydroepiandrosterone sulphate (DHEAS), FT, luteinising hormone (LH) and free androgen index (FAI) were not significant between the two groups (P > 0.05). Furthermore, there was a significant decrease in homeostatic assessment of insulin resistance (HOMA-IR) and hirsutism severity in experimental group (P < 0.05). In both groups, the order of menstrual cycles improved significantly (P < 0.05). Conclusions: Doing AHIIT besides drug therapy can be effective for PCOS patients. |
| first_indexed | 2024-12-19T08:47:20Z |
| format | Article |
| id | doaj.art-461a793c7ec143c9855260dd556aff2c |
| institution | Directory Open Access Journal |
| issn | 2008-7802 2008-8213 |
| language | English |
| last_indexed | 2024-12-19T08:47:20Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Preventive Medicine |
| spelling | doaj.art-461a793c7ec143c9855260dd556aff2c2022-12-21T20:28:48ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132019-01-0110118718710.4103/ijpvm.IJPVM_360_18Evaluation of changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training in women with polycystic ovary syndromeZeinab SamadiEffat BambaeichiMahboubeh ValianiZahra ShahshahanBackground: Polycystic ovary syndrome (PCOS) is a polygenic endocrine disorder in women of reproductive ages which will lead to infertility. This study is aimed to determine changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training (AHIIT) in women with PCOS. Methods: Thirty patients with PCOS having age between 20 and 35 and body mass index (BMI) ≥30 kg/m2 in obstetrics and gynaecology clinics in Isfahan were selected based on Rotterdam Diagnostic Criteria. They were randomly divided into experimental (AHIIT + metformin, N = 15) and control groups (metformin, N = 15). The exercises were done for 12 weeks, three sessions of 20 minutes. Metformin (1500 mg) was taken daily for 3 consecutive days for 12 weeks. Kolmogorov–Smirnov test, t-test, Covariance and Wilcoxon were applied (P value < 0.05). Results: After 12 weeks, no significant difference was observed in waist-to-hip ratio (WHR), but in AHIIT, the BMI and fat mass significantly decreased and levels of follicle-stimulating hormone (FSH), free testosterone (FT) and sex hormone binding globulin (SHBG) increased compared to control group (P < 0.05). While levels of improvement of total testosterone (TT), dehydroepiandrosterone sulphate (DHEAS), FT, luteinising hormone (LH) and free androgen index (FAI) were not significant between the two groups (P > 0.05). Furthermore, there was a significant decrease in homeostatic assessment of insulin resistance (HOMA-IR) and hirsutism severity in experimental group (P < 0.05). In both groups, the order of menstrual cycles improved significantly (P < 0.05). Conclusions: Doing AHIIT besides drug therapy can be effective for PCOS patients.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2019;volume=10;issue=1;spage=187;epage=187;aulast=Samadiahiithyperandrogenemiahirsutismmenstrualpcos |
| spellingShingle | Zeinab Samadi Effat Bambaeichi Mahboubeh Valiani Zahra Shahshahan Evaluation of changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training in women with polycystic ovary syndrome International Journal of Preventive Medicine ahiit hyperandrogenemia hirsutism menstrual pcos |
| title | Evaluation of changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training in women with polycystic ovary syndrome |
| title_full | Evaluation of changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training in women with polycystic ovary syndrome |
| title_fullStr | Evaluation of changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training in women with polycystic ovary syndrome |
| title_full_unstemmed | Evaluation of changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training in women with polycystic ovary syndrome |
| title_short | Evaluation of changes in levels of hyperandrogenism, hirsutism and menstrual regulation after a period of aquatic high intensity interval training in women with polycystic ovary syndrome |
| title_sort | evaluation of changes in levels of hyperandrogenism hirsutism and menstrual regulation after a period of aquatic high intensity interval training in women with polycystic ovary syndrome |
| topic | ahiit hyperandrogenemia hirsutism menstrual pcos |
| url | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2019;volume=10;issue=1;spage=187;epage=187;aulast=Samadi |
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